Antifungal Activity of Human Cathelicidin LL-37, a Membrane Disrupting Peptide, by Triggering Oxidative Stress and Cell Cycle Arrest in Candida auris

IA Rather, JSM Sabir, AH Asseri, S Ali - Journal of Fungi, 2022 - mdpi.com
Candida auris, an evolving multidrug-resistant pathogenic yeast, is known for causing
severe invasive infections associated with high mortality rates in hospitalized individuals …

Antifungal action of human cathelicidin fragment (LL13–37) on Candida albicans

JH Wong, TB Ng, A Legowska, K Rolka, M Hui, CH Cho - Peptides, 2011 - Elsevier
Human cathelicidin LL37 and its fragments LL13–37 and LL17–32 exhibited similar
potencies in inhibiting growth of the yeast Candida albicans. After treatment with 0.5 μM and …

Derivates of the Antifungal Peptide Cm-p5 Inhibit Development of Candida auris Biofilms In Vitro

D Kubiczek, H Raber, M Gonzalez-García… - Antibiotics, 2020 - mdpi.com
Growth in biofilms as a fascinating and complex microbial lifestyle has become widely
accepted as one of the key features of pathogenic microbes, to successfully express their full …

Fluconazole-resistant Candida auris is susceptible to salivary histatin 5 killing and to intrinsic host defenses

RU Pathirana, J Friedman, HL Norris… - Antimicrobial agents …, 2018 - Am Soc Microbiol
Candida auris is a newly identified species causing invasive candidemia and candidiasis. It
has broad multidrug resistance (MDR) not observed for other pathogenic Candida species …

Identification of Off-Patent Compounds That Present Antifungal Activity Against the Emerging Fungal Pathogen Candida auris

HC De Oliveira, MC Monteiro, SA Rossi… - Frontiers in cellular …, 2019 - frontiersin.org
Candida auris is an emerging fungal pathogen of great concern among the scientific
community because it is causing an increasing number of hospital outbreaks of difficult …

The emerging pathogen Candida auris: growth phenotype, virulence factors, activity of antifungals, and effect of SCY-078, a novel glucan synthesis inhibitor, on …

E Larkin, C Hager, J Chandra… - Antimicrobial agents …, 2017 - Am Soc Microbiol
Candida auris, a new multidrug-resistant Candida spp. which is associated with invasive
infection and high rates of mortality, has recently emerged. Here, we determined the …

Echinocandins as Biotechnological Tools for Treating Candida auris Infections

ES Cândido, F Affonseca, MH Cardoso, OL Franco - Journal of Fungi, 2020 - mdpi.com
Candida auris has been reported in the past few years as an invasive fungal pathogen of
high interest. Its recent emergence in healthcare-associated infections triggered the efforts of …

Discovery of a new chemical scaffold for the treatment of superbug Candida auris infections

J Tu, T Zhu, Q Wang, W Yang, Y Huang… - Emerging Microbes & …, 2023 - Taylor & Francis
Candida auris has emerged as a serious threat of public health and caused global epidemic
due to multi-drug resistance, remarkable transmissibility and high mortality. To tackle the …

Protective Efficacy of Anti-Hyr1p Monoclonal Antibody against Systemic Candidiasis Due to Multi-Drug-Resistant Candida auris

S Singh, A Barbarino, EG Youssef, D Coleman… - Journal of Fungi, 2023 - mdpi.com
Candida auris is a multi-drug-resistant fungal pathogen that can survive outside the host and
can easily spread and colonize the healthcare environment, medical devices, and human …

Emerging and future strategies in the management of recalcitrant Candida auris

N Bandara, L Samaranayake - Medical Mycology, 2022 - academic.oup.com
Candida auris is an emerging, multi drug resistant fungal pathogen that has caused
infectious outbreaks in over 45 countries since its first isolation over a decade ago, leading …