Diabetic kidney disease is the most frequent cause of end-stage renal disease. This implies
failure of current therapeutic approaches based on renin-angiotensin system (RAS) …

Despite improvements in glycaemic and blood pressure control, and the efficacy of renin–
angiotensin system (RAS) blockade for proteinuria reduction, diabetic nephropathy is the …

Introduction: The age-standardized death rate from diabetic kidney disease increased by
106% from 1990 to 2013, indicating that novel therapeutic approaches are needed, in …

Background: Diabetic nephropathy is one of the main causes of end-stage renal disease
(ESRD) and is associated with elevated cardiovascular morbidity and mortality. Objective …

Diabetic nephropathy is rapidly becoming the major cause of end-stage renal disease and
cardiovascular mortality worldwide. Standard of care therapies include strict glycemic control …

Diabetic nephropathy is a leading cause of end-stage renal disease worldwide. The
mainstay of treatment has been glycemic control and blood pressure lowering using agents …

Despite increasing awareness and great strides in treatment options, diabetes continues to
be a global epidemic currently affecting well above 400 million individuals worldwide. This …

Diabetic kidney disease is the most frequent cause of kidney failure, accounting for half of all
cases worldwide. Moreover, deaths from diabetic kidney disease increased 106% between …

Diabetic nephropathy remains the most common cause of end-stage renal disease
worldwide. The current standard of therapy for diabetic nephropathy involves stringent blood …

Diabetic nephropathy (DN) is the leading cause of end-stage renal disease (ESRD)
worldwide. Its pathogenesis encompasses functional alterations involving elevated …