Natural product/diet-based regulation of macrophage polarization: Implications in treatment of inflammatory-related diseases and cancer
Macrophages are phagocytic cells with important physiological functions, including the
digestion of cellular debris, foreign substances, and microbes, as well as tissue …
digestion of cellular debris, foreign substances, and microbes, as well as tissue …
Natural products targeting macrophages in tumor microenvironment are a source of potential antitumor agents
QP Liu, YY Chen, P An, K Rahman, X Luan, H Zhang - Phytomedicine, 2023 - Elsevier
Background Macrophages are one of the major cell types in the immune system and are
closely related to tumor development, which can be polarized into M1 type with anti-tumor …
closely related to tumor development, which can be polarized into M1 type with anti-tumor …
Chemopreventive effects of phytochemicals and medicines on M1/M2 polarized macrophage role in inflammation-related diseases
YC Koh, G Yang, CS Lai, M Weerawatanakorn… - International Journal of …, 2018 - mdpi.com
Macrophages can polarize into two different states (M1 and M2), which play contrasting
roles during pathogenesis or tissue damage. M1 polarized macrophages produce pro …
roles during pathogenesis or tissue damage. M1 polarized macrophages produce pro …
Diverse macrophages polarization in tumor microenvironment
I Rhee - Archives of pharmacal research, 2016 - Springer
Macrophages are traditional innate immune cells that play critical roles in the clearance of
pathogens and the maintenance of tissue homeostasis. Accumulating evidence proves that …
pathogens and the maintenance of tissue homeostasis. Accumulating evidence proves that …
Macrophage polarization by phytotherapy in the tumor microenvironment
AM Saeedifar, G Mosayebi, A Ghazavi… - Phytotherapy …, 2021 - Wiley Online Library
Several signaling pathways were involved in M1 (classic) and M2 (alternative) macrophage
polarization. Disruption of M2‐related signaling pathways and improvement of M1‐related …
polarization. Disruption of M2‐related signaling pathways and improvement of M1‐related …
Metabolism and polarization regulation of macrophages in the tumor microenvironment
J Wang, S Mi, M Ding, X Li, S Yuan - Cancer letters, 2022 - Elsevier
The occurrence and development of tumors depend on the tumor microenvironment (TME),
which consists of various types of cellular and acellular components. Tumor-associated …
which consists of various types of cellular and acellular components. Tumor-associated …
Recent advancement on development of drug-induced macrophage polarization in control of human diseases
L Wang, Q Lu, W Gao, S Yu - Life sciences, 2021 - Elsevier
Macrophages, an important part of human immune system, possess a high plasticity and
heterogeneity (macrophage polarization) as classically activated macrophages (M1) and …
heterogeneity (macrophage polarization) as classically activated macrophages (M1) and …
M1 and M2 macrophage polarization and potentially therapeutic naturally occurring compounds
Macrophages, as crucial cellular components of innate immunity, are characterized by
possessing high plasticity and an abnormal ability to differentiate in response to numerous …
possessing high plasticity and an abnormal ability to differentiate in response to numerous …
Natural products for regulating macrophages M2 polarization
Z Chang, Y Wang, C Liu, W Smith… - Current Stem Cell …, 2020 - ingentaconnect.com
Macrophages M2 polarization have been taken as an anti-inflammatory progression during
inflammation. Natural plant-derived products, with potential therapeutic and preventive …
inflammation. Natural plant-derived products, with potential therapeutic and preventive …
Research advances on signaling pathways regulating the polarization of tumor-associated macrophages in lung cancer microenvironment
W Li, Q Yuan, M Li, X He, C Shen, Y Luo, Y Tai… - Frontiers in …, 2024 - frontiersin.org
Lung cancer (LC) is one of the most common cancer worldwide. Tumor-associated
macrophages (TAMs) are important component of the tumor microenvironment (TME) and …
macrophages (TAMs) are important component of the tumor microenvironment (TME) and …
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