In order to analyze the efficiency of interphase FISH for the detection and monitoring of Ph+
cells in chronic myelogenous leukemia (CML) under interferon (IFN) treatment, the following …

We used two-color fluorescence in situ hybridization (FISH) to detect BCR/ABL fusion in
interphase nuclei in bone marrow of 17 patients with chronic myeloid leukemia (CML) before …

We investigated a new method using fluorescence in situ hybridization and DNA probes that
span the common breakpoints of t (9; 22)(q34; q11. 2) and that detect double BCR/ABL …

We describe the use of the fluorescence in situ hybridization (FISH) technique to detect
residual Philadelphia chromosome-positive (Ph+) cells in a patient with blastic phase …

Philadelphia (Ph) chromosome or the bcr/abl fusion gene is the hallmark of chronic myeloid
leukemia (CML) and serves as a prognostic marker during its treatment. Its detection has …

Background: Several attempts have been made to determine whether interphase
fluorescence in situ hybridization (I-FISH) on bone marrow or peripheral blood specimens is …

For the diagnosis of CML and for monitoring of treatment response the detection of the t (9;
22)(q34; q11) or the BCR-ABL rearrangement is necessary. Chromosome banding analysis …

Chronic myeloid leukemia is a clonal stem cell disorder associated with the Philadelphia
(Ph) translocation [t (9; 22)(q34; q11)]. As a result of the Ph translocation, parts of the ABL …

PURPOSE: Standard G-band cytogenetic analysis (CG) provides information on
approximately 25 metaphases for monitoring the presence of Philadelphia chromosome …

Conventional cytogenetic analysis (CCA) is the standard method for monitoring of the
Philadelphia (Ph) chromosome in chronic myeloid leukemia (CML). Evaluation of breakpoint …