Microbial Biosynthesis of Chrysazin Derivatives in Recombinant Escherichia coli and Their Biological Activities

PB Poudel, D Dhakal, RT Magar, JK Sohng - Molecules, 2022 - mdpi.com
Anthraquinone and its derivatives show remarkable biological properties such as
anticancer, antibacterial, antifungal, and antiviral activities. Hence, anthraquinones …

Microbial Biosynthesis of Antibacterial Chrysoeriol in Recombinant Escherichia coli and Bioactivity Assessment

P Bashyal, P Parajuli, RP Pandey, JK Sohng - Catalysts, 2019 - mdpi.com
Various flavonoid derivatives including methoxylated flavones display remarkable biological
activities. Chrysoeriol is a methoxylated flavone of great scientific interest because of its …

Facile synthesis and biological evaluation of chrysin derivatives

N Omonga, Z Zia, H Ghanbour… - Journal of Chemical …, 2021 - journals.sagepub.com
In this paper, novel synthetic methods, including microwave O-alkylation, were used to
produce several chrysin derivatives. These compounds were purified, characterised and …

[HTML][HTML] Synthesis of new chrysin derivatives with substantial antibiofilm activity

S Bhowmik, P Anand, R Das, T Sen, Y Akhter… - Molecular Diversity, 2021 - Springer
Multidrug resistance mechanism of microorganisms towards conventional antimicrobials
nowadays faces a common health problem. So, searching and development of new …

[HTML][HTML] Synthesis and cytotoxicity of novel chrysin derivatives

K Hu, W Wang, H Cheng, SS Pan, J Ren - Medicinal Chemistry Research, 2011 - Springer
A series of chrysin derivatives 8a–8v were prepared and tested in vitro against HCT-116
(human colon cancer cell line), Hela (human cervical carcinoma cell line), DU-145 (human …

Microbial synthesis of non-natural anthraquinone glucosides displaying superior antiproliferative properties

TTH Nguyen, RP Pandey, P Parajuli, JM Han, HJ Jung… - Molecules, 2018 - mdpi.com
Anthraquinones, naturally occurring bioactive compounds, have been reported to exhibit
various biological activities, including anti-inflammatory, antiviral, antimicrobial, and …

Synthesis and biological evaluation of novel C (7) modified chrysin analogues as antibacterial agents

KS Babu, TH Babu, PV Srinivas, KH Kishore… - Bioorganic & medicinal …, 2006 - Elsevier
The natural product, chrysin (5, 7-dihydroxy flavone), obtained from Oroxylum indicum,
exhibits numerous biological activities including anticancer, anti-inflammatory, and …

Synthesis and molecular docking studies of chrysin derivatives as antibacterial agents

X Li, Y Cai, F Yang, Q Meng - Medicinal Chemistry Research, 2017 - Springer
In order to search for drugs with excellent antibacterial activities, a series of novel chrysin
derivatives were designed, synthesized, and evaluated as antibacterial agents. Results of …

Synthesis, characterization and antimicrobial activity of novel xanthene sulfonamide and carboxamide derivatives

M Kaya, E Demir, H Bekci - Journal of enzyme inhibition and …, 2013 - Taylor & Francis
Xanthene intermediates 4a and 4b were obtained from the reduction of nitro xanthene
derivatives 3a and 3b which were synthesized via condensation of dimedone with m …

Total synthesis and structure revision of chrysamide B

J Chen, J Li, L Zhu, X Peng, Y Feng, Y Lu… - Organic Chemistry …, 2018 - pubs.rsc.org
Total synthesis of the originally proposed chrysamide B (2) is described, which features a
convergent assembly of the chiral piperazine core and epoxy-acid. Mismatched …