Proteomic analysis of liver mitochondria of apolipoprotein E knockout mice treated with metformin
A Stachowicz, M Suski, R Olszanecki, J Madej… - Journal of …, 2012 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is strongly associated with insulin resistance.
Metformin, a widely known anti-diabetic drug, used for patients with type 2 diabetes mellitus …
Metformin, a widely known anti-diabetic drug, used for patients with type 2 diabetes mellitus …
Quantitative proteomic and functional analysis of liver mitochondria from high fat diet (HFD) diabetic mice
Y Guo, M Darshi, Y Ma, GA Perkins, Z Shen… - Molecular & Cellular …, 2013 - ASBMB
Insulin resistance plays a major role in the development of type 2 diabetes and obesity and
affects a number of biological processes such as mitochondrial biogenesis. Though …
affects a number of biological processes such as mitochondrial biogenesis. Though …
Influence of metformin on mitochondrial subproteome in the brain of apoE knockout mice
M Suski, R Olszanecki, Ł Chmura, A Stachowicz… - European Journal of …, 2016 - Elsevier
Neurodegenerative diseases are the set of progressive, age-related brain disorders,
characterized by an excessive accumulation of mutant proteins in the certain regions of the …
characterized by an excessive accumulation of mutant proteins in the certain regions of the …
Proteomic analysis of changes in protein expression in liver mitochondria in apoE knockout mice
M Suski, R Olszanecki, J Madej, J Totoń-Żurańska… - Journal of …, 2011 - Elsevier
The involvement of both apolipoprotein E (apoE) and mitochondria in lipid metabolism is
widely recognized, however there is surprisingly scarce data about the putative …
widely recognized, however there is surprisingly scarce data about the putative …
Hepatic mitochondrial defects in a nonalcoholic fatty liver disease mouse model are associated with increased degradation of oxidative phosphorylation subunits
Nonalcoholic fatty liver disease (NAFLD) is associated with hepatic mitochondrial
dysfunction characterized by reduced ATP synthesis. We applied the 2 H 2 O-metabolic …
dysfunction characterized by reduced ATP synthesis. We applied the 2 H 2 O-metabolic …
Proteome, phosphoproteome, and hydroxyproteome of liver mitochondria in diabetic rats at early pathogenic stages
It has been proposed that mitochondrial dysfunction is involved in the pathogenesis of type 2
diabetes (T2D). To dissect the underlying mechanisms, we performed a multiplexed …
diabetes (T2D). To dissect the underlying mechanisms, we performed a multiplexed …
Protein profiling and functional analysis of liver mitochondria from rats with nonalcoholic steatohepatitis
Y You, Y Zhang, Y Lu, K Hu, X Qu… - Molecular …, 2017 - spandidos-publications.com
Mitochondrial dysfunction is closely associated with the pathogenesis of nonalcoholic
steatohepatitis (NASH). The aim of the present study was to comprehensively determine …
steatohepatitis (NASH). The aim of the present study was to comprehensively determine …
Proteomic approaches to identify and characterize alterations to the mitochondrial proteome in alcoholic liver disease
Mitochondrial dysfunction is recognized as a contributing factor to a number of diseases,
including chronic alcohol-induced hepatotoxicity. Although there is a detailed understanding …
including chronic alcohol-induced hepatotoxicity. Although there is a detailed understanding …
Tissue-specific remodeling of the mitochondrial proteome in type 1 diabetic akita mice
H Bugger, D Chen, C Riehle, J Soto, HA Theobald… - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE To elucidate the molecular basis for mitochondrial dysfunction, which has been
implicated in the pathogenesis of diabetes complications. RESEARCH DESIGN AND …
implicated in the pathogenesis of diabetes complications. RESEARCH DESIGN AND …
Mitochondrial molecular pathophysiology of nonalcoholic fatty liver disease: a proteomics approach
N Nuño-Lámbarri, VJ Barbero-Becerra, M Uribe… - International journal of …, 2016 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is a chronic liver condition that can progress to
nonalcoholic steatohepatitis, cirrhosis and cancer. It is considered an emerging health …
nonalcoholic steatohepatitis, cirrhosis and cancer. It is considered an emerging health …
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