Each year, 500,000 patients are treated with radiotherapy for head and neck cancer,
resulting in relatively high survival rates. However, in 40% of patients, quality of life is …

Purpose Radiation therapy for head and neck cancer frequently leads to salivary gland
damage and subsequent xerostomia. The radiation response of the parotid glands of rats …

Oral Diseases (2011) 17, 143–153 Hyposalivation underlying xerostomia after radiotherapy
is still a major problem in the treatment of head and neck cancer. Stem cell therapy may …

Radiation‐induced hyposalivation is still a major problem after radiotherapy for head and
neck cancer. Current and promising new thoughts to reduce or salvage radiation damage to …

BACKGROUND: Stem cell therapy could be a potential way for reducing radiation-induced
hyposalivation and improving the patient's quality of life. However, the identification and …

Dysfunction of the salivary gland and irreversible hyposalivation are the main side effects of
radiotherapy treatment for head and neck cancer leading to a drastic decrease of the quality …

Head and neck cancer is the fifth most common malignancy and accounts for 3% of all new
cancer cases each year. Despite relatively high survival rates, the quality of life of these …

Adult stem cells are often touted as therapeutic agents in the regenerative medicine field,
however data detailing both the engraftment and functional capabilities of solid tissue …

Treatment for most patients with head and neck cancers includes ionizing radiation. A
consequence of this treatment is irreversible damage to salivary glands (SGs), which is …

Background The most manifest long-term consequences of radiation therapy in the head
and neck cancer patient are salivary gland hypofunction and a sensation of oral dryness …