[HTML][HTML] [11C]metomidate PET-CT versus adrenal vein sampling for diagnosing surgically curable primary aldosteronism: a prospective, within-patient trial

X Wu, R Senanayake, E Goodchild, WA Bashari… - Nature Medicine, 2023 - nature.com
Primary aldosteronism (PA) due to a unilateral aldosterone-producing adenoma is a
common cause of hypertension. This can be cured, or greatly improved, by adrenal surgery …

11C‐Metomidate PET/CT is a useful adjunct for lateralization of primary aldosteronism in routine clinical practice

PM O'Shea, D O'Donoghue, W Bashari… - Clinical …, 2019 - Wiley Online Library
Objective To describe clinical practice experience of 11C‐Metomidate PET/CT as an adjunct
to adrenal vein sampling (AVS) in the lateralization of aldosterone‐producing adenomas …

Functional imaging with 11C-metomidate PET for subtype diagnosis in primary aldosteronism

M Soinio, AK Luukkonen, M Seppänen… - European journal of …, 2020 - academic.oup.com
Abstract Objective Endocrine Society guidelines recommend adrenal venous sampling
(AVS) in primary aldosteronism (PA) if adrenalectomy is considered. We tested whether …

Approach to the patient with primary aldosteronism: utility and limitations of adrenal vein sampling

AF Turcu, R Auchus - The Journal of Clinical Endocrinology & …, 2021 - academic.oup.com
Several studies over the past 3 decades document a higher prevalence of primary
aldosteronism (PA) among hypertensive patients than generally presumed. PA exists as a …

Evaluation of the Sensitivity and Specificity of 11C-Metomidate Positron Emission Tomography (PET)-CT for Lateralizing Aldosterone Secretion by Conn's Adenomas

TJ Burton, IS Mackenzie, K Balan, B Koo… - The Journal of …, 2012 - academic.oup.com
Context: Identification of unilateral aldosterone-producing (Conn's) adenomas has
traditionally required lateralization by the invasive and technically difficult procedure of …

Adrenal vein sampling versus CT scan to determine treatment in primary aldosteronism: an outcome-based randomised diagnostic trial

T Dekkers, A Prejbisz, LJS Kool… - The lancet Diabetes & …, 2016 - thelancet.com
Background The distinction between unilateral aldosterone-producing adenoma or bilateral
adrenal hyperplasia as causes of primary aldosteronism is usually made by adrenal CT or …

Accuracy of Gallium-68 Pentixafor Positron Emission Tomography–Computed Tomography for Subtyping Diagnosis of Primary Aldosteronism

J Hu, T Xu, H Shen, Y Song, J Yang, A Zhang… - JAMA Network …, 2023 - jamanetwork.com
Importance Adrenal vein sampling (AVS) is the recommended procedure for subtyping
primary aldosteronism (PA) as unilateral PA (UPA) or bilateral PA (BPA), with different …

Dynamic testing with high-dose adrenocorticotrophic hormone does not improve lateralization of aldosterone oversecretion in primary aldosteronism patients

GP Rossi, C Ganzaroli, D Miotto, R De Toni… - Journal of …, 2006 - journals.lww.com
Objective Diagnosing aldosterone-producing adenoma (APA) involves a demonstration of
the lateralization of aldosterone oversecretion because adrenal incidentalomas are common …

Discordance between imaging and immunohistochemistry in unilateral primary aldosteronism

AT Nanba, K Nanba, JB Byrd, JJ Shields… - Clinical …, 2017 - Wiley Online Library
Objective Correct subtyping of primary aldosteronism (PA) is essential for good surgical
outcomes. Adrenal vein sampling (AVS) and/or computed tomography (CT) are used for PA …

[HTML][HTML] Laboratory investigation of primary aldosteronism

M Stowasser, PJ Taylor, E Pimenta… - The Clinical …, 2010 - ncbi.nlm.nih.gov
Availability and wider application of the plasma aldosterone/renin ratio (ARR) as a
screening test for primary aldosteronism (PA) has led to the recognition that PA is the most …