In 17 patients with rapid cycling bipolar disorder, time-series analyses detected synchronies
between mood cycles and three lunar cycles that modulate the amplitude of the moon's semi …

In bipolar disorder, episodes of depression and mania are associated with dramatic
disturbances in sleep, which experiments show are likely to contribute to the pathogenesis …

Endogenous rhythms of circalunar periodicity (∼ 29.5 days) and their underlying molecular
and genetic basis have been demonstrated in a number of marine species [1, 2]. In contrast …

Mood disorders are serious diseases that affect a large portion of the population. There have
been many hypotheses put forth over the years to explain the development of major …

Sleep disturbances and dysregulation of circadian rhythms are core elements of bipolar
disorder that might be involved in its pathogenesis. It has been proposed that patients with …

There are two main reasons for the growing interest in the dependence of mood disorders
on the circadian clock and its connected pathways. First, the successful translation of …

Recent longitudinal observations show that human menstrual cycles, sleep‐wake cycles
and manic‐depressive cycles can become synchronized with lunar cycles, but do so in …

Numerous hypotheses have been put forth over the years to explain the development of
bipolar disorder. Of these, circadian rhythm hypotheses have gained much importance of …

Circadian clocks are present in nearly all tissues of an organism, including the brain. The
brain is not only the site of the master coordinator of circadian rhythms located in the …

Bipolar disorders are associated with circadian deregulations both during acute mood
episodes and during euthymic periods, suggesting that these circadian rhythms may …