Adrenoceptors, or adrenergic receptors, can be defined as the cell receptors which respond
to the physiological agonists noradrenaline and adrenaline by producing a response in the …

The area of research encompassing a-adrenoceptors and a-adrenergic drugs has
undergone a rapid growth during the past several years. This stems in part from the …

The proliferation of receptor subtypes based on differences in amino acid sequence does
not necessurily coincide with fun~ fiona~ differences. Tlze~~~~ er of-~~-adrenoce~ tor s …

There are currently some experimental observations which point toward a new classification
of alpha-adrenoceptors, not only in terms of the recognition site, but also as initiators of …

Publisher Summary This chapter discusses the pharmacology and structure–activity
relationships of α 2-adrenoceptor antagonists. The α-adrenoceptor was originally …

It has been nearly ten years since the first suggestion that both α 1-[1, 2] and α 2-[3, 4]
adrenoceptors could be further subdivided into additional subtypes. Shortly after this time …

Different studies have led to our present knowledge of the membrane receptors responsible
for mediating the responses to the endogenous catecholamines. These receptors were …

292 KUNOS {3-receptor subgroups (7, 8) and by a lack of homogeneity among a.-
adrenoceptors in different tissues (9-11). However, the basic distinction between 0.-and {3 …

This review examines the functions of α 1-adrenoceptor subtypes, particularly in terms of
contraction of smooth muscle. There are 3 subtypes of α 1-adrenoceptor, α 1A-α 1B-and α …

The concept of pre-and postjunctionally located a adrenoceptors, as well as the more recent
subdivision into ax and a2 subtypes, has initiated duringthe last decade a renaissance of …