Alzheimer's disease (AD) is considered to be the most common cause of dementia and is an
incurable, progressive neurodegenerative disorder. Current treatment of the disease …

Alzheimer Disease (AD) is a neurodegenerative disease characterized by two
neuropathological hallmarks: extracellular deposition of amyloid plaques and intracellular …

Alzheimer's disease (AD) is characterized by a chronic and progressive neurodegenerative
process resulting from the intracellular and extracellular accumulation of fibrillary proteins …

Objective: To review the different pharmacological approaches to the cognitive, functional,
and behavioural manifestations of Alzheimer disease (AD). Methods: We searched and …

Alzheimer's disease (AD) is a major form of senile dementia, characterized by progressive
memory and neuronal loss combined with cognitive impairment. AD is the most common …

Alzheimer's disease is the most common cause of dementia in elderly people. Research into
Alzheimer's disease therapy has been at least partly successful in terms of developing …

Alzheimer's disease (AD) is a devastating neurological disorder that affects more than 37
million people worldwide1. The economic burden of AD is massive; in the United States …

ABSTRACT Introduction Currently available Alzheimer's disease (AD) therapeutics are only
symptomatic, targeting cholinergic and glutamatergic neurotransmissions. Several putative …

Alzheimer disease (AD) drug development has a high failure rate. Drug development
decision making can be improved based on lessons learned from past trials. Improved …

Dementia is an acquired global impairment of cognitive capacities. Approximately 5% of
people aged over 65 yr are affected by dementia, and some 70% of cases are thought to be …