Low-dose oral contraceptives and acquired resistance to activated protein C: a randomised cross-over study
J Rosing, S Middeldorp, J Curvers, MCL GDlig… - The Lancet, 1999 - thelancet.com
Background We have reported previously that, compared with use of second-generation oral
contraceptives, the use of third-generation oral contraceptives is associated with increased …
contraceptives, the use of third-generation oral contraceptives is associated with increased …
Hormone replacement therapy and acquired resistance to activated protein C: results of a randomized, double‐blind, placebo‐controlled trial
E Høibraaten, MC Mowinckel… - British journal of …, 2001 - Wiley Online Library
Recent studies suggest that low‐dose oral contraceptives may cause acquired resistance to
activated protein C (APC). The aims of this study were to determine whether hormone …
activated protein C (APC). The aims of this study were to determine whether hormone …
Oral contraceptives and venous thrombosis: different sensitivities to activated protein C in women using second‐and third‐generation oral contraceptives
J Rosing, G Tans, GAF Nicolaes… - British journal of …, 1997 - Wiley Online Library
Epidemiological studies have shown that women who use third‐generation oral
contraceptives (OC) containing desogestrel, gestodene or norgestimate have a higher risk of …
contraceptives (OC) containing desogestrel, gestodene or norgestimate have a higher risk of …
Activated protein C resistance determined with a thrombin generation‐based test predicts for venous thrombosis in men and women
G Tans, A van Hylckama Vlieg… - British journal of …, 2003 - Wiley Online Library
Activated protein C (APC) resistance, determined with a thrombin‐generation‐based APC
resistance test, may explain risk differences of venous thrombosis in users of second‐and …
resistance test, may explain risk differences of venous thrombosis in users of second‐and …
[HTML][HTML] Impact of progestagens on activated protein C (APC) resistance among users of oral contraceptives
M Alhenc‐Gelas, G Plu‐Bureau, S Guillonneau… - Journal of thrombosis …, 2004 - Elsevier
Oral contraceptive (OC) use is associated with an increased risk of venous
thromboembolism. Previous data reported higher thrombotic risk in women using third …
thromboembolism. Previous data reported higher thrombotic risk in women using third …
Acquired APC resistance and oral contraceptives: differences between two functional tests
J Curvers, MCLGD Thomassen… - British journal of …, 1999 - Wiley Online Library
Resistance to activated protein C (APC) is often associated with a mutation in factor V (factor
VLeiden). Individuals without factor VLeiden who exhibit a response in functional APC …
VLeiden). Individuals without factor VLeiden who exhibit a response in functional APC …
Effect of second- and third-generation oral contraceptives on the protein C system in the absence or presence of the factor VLeiden mutation: a randomized trial
JM Kemmeren, A Algra, JCM Meijers, G Tans… - Blood, 2004 - ashpublications.org
A plausible mechanism to explain thrombotic risk differences associated with the use of
second-and third-generation oral contraceptives (OCs), particularly in carriers of factor …
second-and third-generation oral contraceptives (OCs), particularly in carriers of factor …
[HTML][HTML] Different effects of oral contraceptives containing different progestogens on protein S and tissue factor pathway inhibitor
H Van Vliet, RM Bertina, AEA Dahm… - Journal of Thrombosis …, 2008 - Elsevier
Background: Oral contraceptives (OC) containing different types of progestogens induce
different sensitivities to activated protein C (APC) measured with the thrombin generation …
different sensitivities to activated protein C (APC) measured with the thrombin generation …
Resistance to activated protein C in healthy women taking oral contraceptives
O Olivieri, S Friso, F Manzato, A Guella… - British Journal of …, 1995 - Wiley Online Library
Resistance to activated protein C (APC) is at present considered the most frequent
laboratory abnormality in patients with deep‐vein thrombosis. An increased risk for venous …
laboratory abnormality in patients with deep‐vein thrombosis. An increased risk for venous …
Increased risk of venous thrombosis in oral-contraceptive users who are carriers of factor V Leiden mutation
JP Vandenbroucke, T Koster, FR Rosendaal, E Briët… - The Lancet, 1994 - Elsevier
We investigated whether the occurrence of venous thrombosis in young women who use
oral contraceptives might be explained by the factor V Leiden mutation, which leads to …
oral contraceptives might be explained by the factor V Leiden mutation, which leads to …
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