Long-acting therapeutic delivery systems for the treatment of gliomas

S Padmakumar, MM Amiji - Advanced Drug Delivery Reviews, 2023 - Elsevier
Despite the emergence of cutting-edge therapeutic strategies and tremendous progress in
research, a complete cure of glioma remains elusive. The heterogenous nature of tumor …

Current developments in targeted drug delivery systems for glioma

D Patel, S Wairkar, MC Yergeri - Current Pharmaceutical …, 2020 - ingentaconnect.com
Background: Glioma is one of the most commonly observed tumours, representing about
75% of brain tumours in the adult population. Generally, glioma treatment includes surgical …

Frontiers in the treatment of glioblastoma: Past, present and emerging

TI Janjua, P Rewatkar, A Ahmed-Cox, I Saeed… - Advanced drug delivery …, 2021 - Elsevier
Glioblastoma (GBM) is one of the most aggressive cancers of the brain. Despite extensive
research over the last several decades, the survival rates for GBM have not improved and …

Insights into multifunctional nanoparticle-based drug delivery systems for glioblastoma treatment

M Khan, S Sherwani, S Khan, S Alouffi, M Alam… - Molecules, 2021 - mdpi.com
Glioblastoma (GB) is an aggressive cancer with high microvascular proliferation, resulting in
accelerated invasion and diffused infiltration into the surrounding brain tissues with very low …

Injectable local drug delivery systems for glioblastoma: a systematic review and meta-analysis of progress to date

Y Wang, C Bastiancich, B Newland - Biomaterials Science, 2023 - pubs.rsc.org
Glioblastoma (GBM) is an aggressive malignant cancer associated with bleak prognosis and
high mortality. The current standard of care for GBM is maximum surgical resection plus …

Drug and cell encapsulation: alternative delivery options for the treatment of malignant brain tumors

SV Bhujbal, P de Vos, SP Niclou - Advanced drug delivery reviews, 2014 - Elsevier
Malignant brain tumors including glioblastoma are incurable cancers. Over the last years a
number of promising novel treatment approaches have been investigated including the …

[HTML][HTML] Drug-loaded nanoparticle systems and adult stem cells: a potential marriage for the treatment of malignant glioma?

B Auffinger, R Morshed, A Tobias, Y Cheng… - Oncotarget, 2013 - ncbi.nlm.nih.gov
Despite all recent advances in malignant glioma research, only modest progress has been
achieved in improving patient prognosis and quality of life. Such a clinical scenario …

[HTML][HTML] Molecular targets and nanoparticulate systems designed for the improved therapeutic intervention in glioblastoma multiforme

MH Akhter, M Rizwanullah, J Ahmad, S Amin… - Drug …, 2021 - thieme-connect.com
Glioblastoma multiforme (GBM) is the most aggressive and fatal CNS related tumors, which
is responsible for about 4% of cancer-related deaths. Current GBM therapy includes surgery …

Advances in drug delivery technology for the treatment of glioblastoma multiforme

GD Cha, T Kang, S Baik, D Kim, SH Choi… - Journal of Controlled …, 2020 - Elsevier
Glioblastoma multiforme (GBM) is a particularly aggressive and malignant type of brain
tumor, notorious for its high recurrence rate and low survival rate. The treatment of GBM is …

Localized drug delivery systems in high‐grade glioma therapy—from construction to application

M Hauck, D Hellmold, C Kubelt… - Advanced …, 2022 - Wiley Online Library
High‐grade gliomas are the most common and most malign primary brain tumors. Current
therapy approaches only reach unsatisfactory results, still not providing a long‐lasting time …