[HTML][HTML] A more novel and powerful prognostic gene signature of lung adenocarcinoma determined from the immune cell infiltration landscape

C Ma, F Li, Z He, S Zhao - Frontiers in Surgery, 2022 - frontiersin.org
Background Lung adenocarcinoma (LUAD) is the leading histological subtype of lung
cancer worldwide, causing high mortality each year. The tumor immune cell infiltration (ICI) …

[HTML][HTML] Development and validation of a 12-gene immune relevant prognostic signature for lung adenocarcinoma through machine learning strategies

L Xue, G Bi, C Zhan, Y Zhang, Y Yuan, H Fan - Frontiers in oncology, 2020 - frontiersin.org
Background: Although immunotherapy with checkpoint inhibitors is changing the face of
lung adenocarcinoma (LUAD) treatments, only limited patients could benefit from it …

[HTML][HTML] Identification of novel gene signature for lung adenocarcinoma by machine learning to predict immunotherapy and prognosis

J Shu, J Jiang, G Zhao - Frontiers in Immunology, 2023 - frontiersin.org
Background Lung adenocarcinoma (LUAD) as a frequent type of lung cancer has a 5-year
overall survival rate of lower than 20% among patients with advanced lung cancer. This …

[HTML][HTML] Identification of prognostic candidate signatures by systematically revealing transcriptome characteristics in lung adenocarcinoma with differing tumor …

Q Chen, J Ma, X Wang, X Zhu - Aging (Albany NY), 2022 - ncbi.nlm.nih.gov
Accumulated evidence shows that tumor microenvironment plays crucial roles in predicting
clinical outcomes of lung adenocarcinoma (LUAD). The current study aimed to identify some …

[HTML][HTML] Hallmark guided identification and characterization of a novel immune-relevant signature for prognostication of recurrence in stage I–III lung adenocarcinoma

Y Zhang, Z Yang, Y Tang, C Guo, D Lin, L Cheng… - Genes & …, 2023 - Elsevier
The high risk of postoperative mortality in lung adenocarcinoma (LUAD) patients is
principally driven by cancer recurrence and low response rates to adjuvant treatment. Here …

[HTML][HTML] Identification and validation of immune-related gene signature for predicting lymph node metastasis and prognosis in lung adenocarcinoma

R Jia, Z Sui, H Zhang, Z Yu - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
Lung cancer is a serious malignancy, and lung adenocarcinoma (LUAD) is the most
common pathological subtype. Immune-related factors play an important role in lymph node …

[HTML][HTML] A prognostic nomogram combining immune-related gene signature and clinical factors predicts survival in patients with lung adenocarcinoma

C Song, Z Guo, D Yu, Y Wang, Q Wang, Z Dong… - Frontiers in …, 2020 - frontiersin.org
The existence of tumor heterogeneity and complex carcinogenic mechanisms in lung
adenocarcinoma (LUAD) make the most commonly used TNM staging system unable to well …

[HTML][HTML] Screening and identification of four prognostic genes related to immune infiltration and G-protein coupled receptors pathway in lung adenocarcinoma

Y Wang, L Qiu, Y Chen, X Zhang, P Yang… - Frontiers in Oncology, 2021 - frontiersin.org
Background Lung adenocarcinoma (LUAD) is a common malignant tumor with the highest
morbidity and mortality worldwide. The degree of tumor immune infiltration and clinical …

[HTML][HTML] An immune panel signature predicts prognosis of lung adenocarcinoma patients and correlates with immune microenvironment

Y Zhou, L Tang, Y Chen, Y Zhang… - Frontiers in Cell and …, 2021 - frontiersin.org
Background: Lung cancer, especially lung adenocarcinoma (LUAD) with high incidence,
seriously endangers human life. The immune microenvironment is one of the malignant …

Development and validation of an immune‐related prognostic signature in lung adenocarcinoma

S Sun, W Guo, Z Wang, X Wang, G Zhang… - Cancer …, 2020 - Wiley Online Library
Background Lung adenocarcinomas (LUAD) is the most common histological subtype of
lung cancers. Tumor immune microenvironment (TIME) is involved in tumorigeneses …