Bronchodilator reversibility in COPD

NA Hanania, BR Celli, JF Donohue, UJ Martin - Chest, 2011 - Elsevier
COPD is a preventable and treatable disease characterized by airflow limitation that is not
fully reversible. The diagnosis of COPD is based on spirometric evidence of airways …

The forgotten message from gold: FVC is a primary clinical outcome measure of bronchodilator reversibility in COPD

HB Saad, C Préfaut, Z Tabka, A Zbidi… - Pulmonary pharmacology …, 2008 - Elsevier
BACKGROUND: The Global Initiative for Chronic Obstructive Lung Disease (GOLD)
recommends the use of forced expiratory volume in 1s (FEV1) to assess airways …

Assessment of bronchodilator efficacy in symptomatic COPD: is spirometry useful?

DE O'Donnell - Chest, 2000 - Elsevier
Bronchodilator therapy in COPD is deemed successful if it improves ventilatory mechanics to
a degree where effective symptom alleviation and increased exercise capacity are achieved …

Evaluation of acute bronchodilator reversibility in patients with symptoms of GOLD stage I COPD

DE O'donnell, P Laveneziana, J Ora, KA Webb… - Thorax, 2009 - thorax.bmj.com
Background: Patients with symptoms of GOLD stage I chronic obstructive pulmonary disease
(COPD) can have significant abnormalities of ventilatory mechanics with greater exertional …

Bronchodilator reversibility in chronic obstructive pulmonary disease: use and limitations

PMA Calverley, P Albert, PP Walker - The lancet Respiratory …, 2013 - thelancet.com
The change in forced expiratory volume in 1 s (FEV 1) after administration of a short-acting
bronchodilator has been widely used to identify patients with chronic obstructive pulmonary …

Bronchodilator reversibility, exercise performance and breathlessness in stable chronic obstructive pulmonary disease

JG Hay, P Stone, J Carter, S Church… - European …, 1992 - Eur Respiratory Soc
Partial bronchodilator reversibility can be demonstrated in many patients with stable chronic
obstructive pulmonary disease (COPD), but its relevance to exercise capacity and symptoms …

Bronchodilator reversibility testing in chronic obstructive pulmonary disease

PMA Calverley, PS Burge, S Spencer, JA Anderson… - Thorax, 2003 - thorax.bmj.com
Background: A limited or absent bronchodilator response is used to classify chronic
obstructive pulmonary disease (COPD) and can determine the treatment offered. The …

The role of long-acting bronchodilators in the management of stable COPD

DP Tashkin, CB Cooper - Chest, 2004 - Elsevier
Bronchodilators form the foundation of symptomatic treatment of COPD. Several long-acting
bronchodilators are now available for use in COPD, but publications of large-scale studies of …

Relationship between improved airflow limitation and changes in airway calibre induced by inhaled anticholinergic agents in COPD

M Hasegawa, H Makita, Y Nasuhara, N Odajima… - Thorax, 2009 - thorax.bmj.com
Background: Although airflow limitation improved by inhaled anticholinergic drugs varies
among individuals with chronic obstructive pulmonary disease (COPD), the relationship …

Lung function and symptom improvement with fluticasone propionate/salmeterol and ipratropium bromide/albuterol in COPD: response by beta-agonist reversibility

ER Bleecker, A Emmett, G Crater, K Knobil… - Pulmonary pharmacology …, 2008 - Elsevier
This retrospective analysis of data from two multi-center, randomized, double-blind, parallel
group studies compared the efficacy of fluticasone propionate/salmeterol (FSC) 250/50mcg …