Background Biological processes of aging are thought to be modifiable causes of many
different chronic diseases. Measures of biological aging could provide sensitive endpoints …

Measures of biological age and its components have been shown to provide important
information about individual health and prospective change in health as there is clear value …

Quantification of biological aging has been proposed for population surveillance of age-
related decline in system integrity and evaluation of geroprotective therapies. However …

Biomarkers of aging are needed to evaluate proposed treatments to retard aging rates. At
present, the only validated biomarker of aging is maximum life span, which remains …

The geroscience hypothesis posits that therapies to slow biological processes of aging can
prevent disease and extend healthy years of life. To test such “geroprotective” therapies in …

There are many problems in measuring 'biological'age rather than chronological age, not
least the necessity of demonstrating that this measure has validity in terms of better …

Much progress has been made in the past decades in unraveling the mechanisms that are
responsible for aging. The discovery that particular gene mutations in experimental species …

As healthspan and lifespan research breakthroughs have become more commonplace, the
need for valid, practical markers of biological age is becoming increasingly paramount. The …

Methods to quantify biological aging are emerging as new measurement tools for
epidemiology and population science and have been proposed as surrogate measures for …

The Normative Aging Study is a comprehensive interdisciplinary longitudinal study located
in the VA Outpatient Clinic in Boston, Mass. The study was inaugurated in 1963 by the VA …