Immune dysfunction and autoimmunity as pathological mechanisms in autism spectrum disorders

HK Hughes, E Mills Ko, D Rose… - Frontiers in cellular …, 2018 - frontiersin.org
Autism spectrum disorders (ASD) are a group of heterogeneous neurological disorders that
are highly variable and are clinically characterized by deficits in social interactions …

Immune dysregulation in autism spectrum disorder

EY Hsiao - International review of neurobiology, 2013 - Elsevier
Autism spectrum disorder (ASD) is a highly heterogeneous disorder diagnosed based on
the presence and severity of core abnormalities in social communication and repetitive …

The role of immune dysfunction in the pathophysiology of autism

C Onore, M Careaga, P Ashwood - Brain, behavior, and immunity, 2012 - Elsevier
Autism spectrum disorders (ASD) are a complex group of neurodevelopmental disorders
encompassing impairments in communication, social interactions and restricted …

Immune dysfunction and neuroinflammation in autism spectrum disorder

G Bjorklund, K Saad, S Chirumbolo, J Kern… - Acta neurobiologiae …, 2016 - ane.pl
Autism spectrum disorder (ASD) is a complex heterogeneous neurodevelopmental disorder
with a complex pathogenesis. Many studies over the last four decades have recognized …

Immune abnormalities in autism spectrum disorder—could they hold promise for causative treatment?

D Gładysz, A Krzywdzińska, KK Hozyasz - Molecular neurobiology, 2018 - Springer
Autism spectrum disorders (ASD) are characterized by impairments in language and
communication development, social behavior, and the occurrence of stereotypic patterns of …

Immune dysregulation in autism spectrum disorder: what do we know about it?

MA Robinson-Agramonte, E Noris García… - International journal of …, 2022 - mdpi.com
Autism spectrum disorder (ASD) is a group of complex multifactorial neurodevelopmental
disorders characterized by a wide and variable set of neuropsychiatric symptoms, including …

The immune response in autism: a new frontier for autism research

P Ashwood, S Wills… - Journal of leukocyte …, 2006 - academic.oup.com
Autism spectrum disorders (ASD) are part of a broad spectrum of neurodevelopmental
disorders known as pervasive developmental disorders, which occur in childhood. They are …

Evidence supporting an altered immune response in ASD

J Mead, P Ashwood - Immunology letters, 2015 - Elsevier
Autism spectrum disorders (ASD) are neurodevelopmental disorders characterized by
deficits in social interactions, communication, and increased stereotypical repetitive …

Toward an immune-mediated subtype of autism spectrum disorder

CJ McDougle, SM Landino, A Vahabzadeh, J O'Rourke… - Brain research, 2015 - Elsevier
A role for immunological involvement in autism spectrum disorder (ASD) has long been
hypothesized. This review includes four sections describing (1) evidence for a relationship …

Immune dysfunction in autism: a pathway to treatment

M Careaga, J Van de Water, P Ashwood - Neurotherapeutics, 2010 - Elsevier
Autism is a complex and clinically heterogeneous disorder with a spectrum of symptoms.
Clinicians, schools, and service agencies worldwide have reported a dramatic increase in …