Introduction Brain death (BD) is known to compromise graft quality by causing
hemodynamic, metabolic, and hormonal changes. The abrupt reduction of female sex …

OBJECTIVES: Lung transplantation is limited by the systemic repercussions of brain death
(BD). Studies have shown the potential protective role of 17β-estradiol on the lungs. Here …

Background. Brain death (BD) affects the viability of lungs for transplantation. A correlation
exists between high-lung inflammation after BD and the decrease in female sex hormones …

Background Donor sex has been suggested to be a factor influencing organ transplantation
outcome. Sex hormones possess inflammatory and immune-mediating properties; therefore …

Background: The process of brain death (BD) leads to a pro-inflammatory state of the donor
lung, which deteriorates its quality. In an attempt to preserve lung quality …

BACKGROUND Brain death elicits microvascular dysfunction and inflammation, and thereby
compromises lung viability for transplantation. As 17β-estradiol was shown to be anti …

Organ donor's age negatively influences graft survival of organs, increasing risk of
complications. Aging occurs in both men and women; however, the menopause marks a …

Background. The onset of brain death (BD) leads to the deterioration of potential donor
lungs. Methylprednisolone is considered to increase lung oxygenation capacity and …

The viability of donor organs is reduced by hemodynamic and immunologic alterations
caused by brain death (BD). Female rats show higher heart inflammation associated with the …

As a consequence of systemic inflammation caused by ischemia and reperfusion (I/R) due to
aortic occlusion, the lungs can exhibit increased microvascular permeability, local release of …