Molecular Techniques to Detect Disease and Response to Therapy: Minimal Residual Disease

ME Beckner, JA Kant - Molecular Pathology of Hematolymphoid Diseases, 2010 - Springer
Abstract Evaluation for the presence of neoplastic cells or karyotypic abnormalities has
traditionally been performed to monitor therapeutic response of hematolymphoid …

Detection of Minimal Residual Disease

Y Zhou - Practical Lymph Node and Bone Marrow Pathology …, 2020 - Springer
Complete remission for hematolymphoid neoplasms affecting the bone marrow was
traditionally considered to mean absence of morphologically detectable disease in the bone …

Measurable Residual Disease Detection in Hematolymphoid Malignancies: Techniques and Clinical Significance

W Li - 2022 - Springer
Measurable/minimal residual disease (MRD) refers to the small number of malignant cells
remaining in the body of cancer patients during or after treatment. MRD detection is the best …

Minimal residual disease

JJM van Dongen, T Szczepański… - Innovative leukemia …, 2019 - taylorfrancis.com
More sensitive techniques are required for the detection of low frequencies of malignant
cells during and after treatment, ie, detection of minimal residual disease (MRD). In order to …

Detection of minimal residual disease: relevance for diagnosis and treatment of human malignancies

C Hirsch-Ginsberg - Annual review of medicine, 1998 - annualreviews.org
Minimal residual disease (MRD) is the tumor burden that is present after a course of
treatment that has resulted in clinical remission. For hematopoietic malignancies, techniques …

[引用][C] The use of the polymerase chain reaction for the detection of minimal residual malignant disease

RS Negrin, KG Blume - 1991 - ashpublications.org
(BMT) has resulted in the successful treatment of patients with a variety of hemato-lymphoid
malignancies. Despite this success, relapse of the underlying disease has been a persistent …

Prognostic Markers

D Bahler - Molecular Pathology of Hematolymphoid Diseases, 2010 - Springer
The prognosis of hematolymphoid neoplasms varies greatly, not only between different
entities but also among tumors that have the same diagnoses. Clinical variation among …

Use of Bulk Lysing Greatly Increases Cell Recovery in Paucicellular Specimens Submitted for Minimal Residual Disease Studies in Flow Cytometry

B Greig - American Journal of Clinical Pathology, 2015 - academic.oup.com
With the increasing application of flow cytometry to monitor patients who have been
previously diagnosed and treated for a wide range of hematolymphoid neoplasms, detection …

[引用][C] THEME: MOLECULAR DIAGNOSIS OF HEMATOLOGICAL DISORDERS, PART I-Molecular Methods for Minimal Residual Disease Detection in …

C Bartolo, DS Viswanatha - Journal of …, 2001 - Wayne, MI: Clinical Ligand Assay …

[引用][C] Molecular methods for minimal residual disease detection in hematolymphoid diseases: principles and applications

C Bartolo, DS Viswanatha - JOURNAL OF …, 2001 - … ASSAY SOC 3139 S WAYNE RD …