Covering: 2011 up to the end of 2021. Fungal nonribosomal peptides (NRPs) and the
related polyketide–nonribosomal peptide hybrid products (PK–NRPs) are a prolific source of …

Fungal polyketide synthase–nonribosomal peptide synthetase (PKS–NRPS) hybrids
manufacture a wide range of structurally diverse secondary metabolites that play an eminent …

Polyketide synthases (PKSs) and nonribosomal peptide synthetases (NRPSs) each give rise
to a vast array of complex bioactive molecules with further complexity added by the …

The biosynthesis of complex natural products by non-ribosomal peptide synthetases
(NRPSs) and the related polyketide synthases (PKSs) represents a major source of …

Nonribosomal peptides and polyketides are a diverse group of natural products with
complex chemical structures and enormous pharmaceutical potential. They are synthesized …

Nonribosomal peptide synthetases (NRPSs) assemble a large group of structurally and
functionally diverse natural products. While the iterative catalytic mechanism of bacterial …

Nonribosomal peptides (NRPs) are produced by NRP synthetase (NRPS) enzymes that
function as molecular assembly lines. The modular architecture of NRPSs suggests that a …

Nonribosomal peptide synthetases (NRPSs) are involved in the biosynthesis of numerous
peptide and peptide-like natural products that have been exploited in medicine, agriculture …

The structural and catalytic similarities between modular nonribosomal peptide synthetase
(NRPS) and polyketide synthase (PKS) inspired us to search for hybrid NRPS–PKS systems …

Bioactive small molecules that are produced by living organisms, often referred to as natural
products (NPs), historically play a critical role in the context of both medicinal chemistry and …