It is almost 20 years since NNRTIs were identified as a new class of antiretroviral drugs for
the treatment of HIV-1 infection. Although they belong to different and diverse chemical …

Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are promising drugs for the
treatment of HIV when used in combination with other anti-HIV drugs such as nucleoside …

Human immunodeficiency virus (HIV) infection is now pandemic. Targeting HIV-1 reverse
transcriptase (HIV-1 RT) has been considered as one of the most successful targets for the …

Along with nucleoside reverse transcriptase inhibitors (NRTIs) and protease inhibitors (PIs),
nonnucleoside reverse transcriptase inhibitors (NNRTIs) have gained a definitive and …

Non-nucleoside reverse transcriptase inhibitors (NNRTIs) have, in addition to the nucleoside
reverse transcriptase inhibitors (NRTIs) and protease inhibitors (PIs), gained a definitive …

Almost fifteen years ago, the first non-nucleoside reverse transcriptase (RT) inhibitor
(NNRTI) lead compounds have been discovered. Nowadays, three NNRTIs are approved for …

Non‐nucleoside reverse transcriptase (RT) inhibitors (NNRTIs) have become an inherent
ingredient of the drug combination schemes that are currently used in the treatment of …

Non-nucleoside reverse transcriptase inhibitors (NNRTIs) have, in addition to the nucleoside
reverse transcriptase inhibitors (NRTIs) and protease inhibitors (PIs), gained a definitive …

Introduction: Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are essential
components of highly active antiretroviral therapy against HIV-1 infections. Here, we provide …

Twenty-five years ago, nucleoside analog 3′-azidothymidine (AZT) was shown to efficiently
block the replication of HIV in cell culture. Subsequent studies demonstrated that AZT acts …