Dynamic phosphorylation of miRNA biogenesis factor HYL1 by MPK3 involving nuclear–cytoplasmic shuttling and protein stability in Arabidopsis

PK Bhagat, D Verma, K Singh, R Badmi… - International journal of …, 2022 - mdpi.com
MicroRNAs (miRNAs) are one of the prime regulators of gene expression. The recruitment of
hyponastic leaves 1 (HYL1), a double-stranded RNA binding protein also termed as DRB1 …

Hyponastic Leaves 1 interacts with RNA Pol II to ensure proper transcription of microRNA genes

D Bielewicz, J Dolata, M Bajczyk, L Szewc… - Plant and Cell …, 2023 - academic.oup.com
Abstract Hyponastic Leaves 1 (HYL1)[also known as Double-stranded RNA-Binding protein
1 (DRB1)] is a double-stranded RNA-binding protein involved in microRNA (miRNA) …

The N-Terminal Double-Stranded RNA Binding Domains of Arabidopsis HYPONASTIC LEAVES1 Are Sufficient for Pre-MicroRNA Processing

F Wu, L Yu, W Cao, Y Mao, Z Liu, Y He - The Plant Cell, 2007 - academic.oup.com
Abstract Arabidopsis thaliana HYPONASTIC LEAVES1 (HYL1) is a microRNA (miRNA)
biogenesis protein that contains two N-terminal double-stranded RNA binding domains …

[PDF][PDF] The protein phosphatase 4 and SMEK1 complex dephosphorylates HYL1 to promote miRNA biogenesis by antagonizing the MAPK cascade in Arabidopsis

C Su, Z Li, J Cheng, L Li, S Zhong, L Liu, Y Zheng… - Developmental Cell, 2017 - cell.com
Phosphorylation plays an essential role in microRNA (miRNA) processing by regulating co-
factors of the miRNA biogenesis machinery. HYL1 (Hyponastic Leaves 1), a core co-factor in …

Cytoplasmic HYL1 modulates miRNA-mediated translational repression

X Yang, W Dong, W Ren, Q Zhao, F Wu, Y He - The Plant Cell, 2021 - academic.oup.com
MicroRNAs (miRNAs) control various biological processes by repressing target mRNAs. In
plants, miRNAs mediate target gene repression via both mRNA cleavage and translational …

Micro RNA biogenesis factor DRB 1 is a phosphorylation target of mitogen activated protein kinase MPK 3 in both rice and Arabidopsis

B Raghuram, AH Sheikh, Y Rustagi… - The FEBS …, 2015 - Wiley Online Library
Micro RNA (miRNA) biogenesis requires At DRB 1 (double‐stranded RNA binding
protein)/HYL 1 (Hyponastic Leaves1) protein for processing and maturation of mi RNA …

[PDF][PDF] Structure of Arabidopsis HYPONASTIC LEAVES1 and its molecular implications for miRNA processing

SW Yang, HY Chen, J Yang, S Machida, NH Chua… - Structure, 2010 - cell.com
Summary The Arabidopsis HYPONASTIC LEAVES1 (HYL1) is a double-stranded RNA-
binding protein that forms a complex with DICER-LIKE1 (DCL1) and SERRATE to facilitate …

Transcriptome Analyses Revealed Diverse Expression Changes in ago1 and hyl1 Arabidopsis Mutants

Y Kurihara, E Kaminuma, A Matsui… - Plant and cell …, 2009 - academic.oup.com
Abstract MicroRNAs (miRNAs) are 20–24 nucleotide endogenous regulatory molecules
conserved in higher eukaryotes. In Arabidopsis, miRNAs are produced through step-wise …

[HTML][HTML] The SnRK2 kinases modulate miRNA accumulation in Arabidopsis

J Yan, P Wang, B Wang, CC Hsu, K Tang… - PLoS …, 2017 - journals.plos.org
MicroRNAs (miRNAs) regulate gene expression and play critical roles in growth and
development as well as stress responses in eukaryotes. miRNA biogenesis in plants …

[PDF][PDF] Identification of nuclear dicing bodies containing proteins for microRNA biogenesis in living Arabidopsis plants

Y Fang, DL Spector - Current Biology, 2007 - cell.com
MicroRNAs (miRNAs) are important for regulating gene expression in muticellular
organisms. MiRNA processing is a two-step process. In animal cells, the first step is nuclear …