Heparin was discovered 90 years ago, 1 and within 2 decades it was being widely used as
an anticoagulant. 2 The numerous advantages of heparin lend to its broad use including its …

Heparin-induced thrombocytopenia (HIT) is an immune response to heparin that can
progress to severe thrombosis, amputation, and in some cases death. The diagnosis and …

Abstract Heparin-induced thrombocytopenia (HIT), even rare, is a life-threatening, immune-
mediated complication of heparin exposure. It is considered the most severe non-bleeding …

Management of heparin-induced thrombocytopenia : Current Opinion in Hematology
Management of heparin-induced thrombocytopenia : Current Opinion in Hematology Log in or …

BACKGROUND AND OBJECTIVE: There are two types of heparin-induced
thrombocytopenia (HIT). HIT I is characterized by a transitory, slight and asymptomatic …

Heparin, employed clinically for more than 50 years, is still a widely used anticoagulant.
Unfortunately, some patients given this agent develop thrombocytopenia and thrombosis …

Heparin-induced thrombocytopenia is a prothrombotic adverse drug effect induced by
platelet-activating antibodies against multimolecular complexes of platelet factor 4 and …

INTRODUCTION Heparin-induced thrombocytopenia (HIT) presents a unique situation:
heparin causes the very complications that its use was intended to prevent, for example …

Thrombocytopenia is a relatively frequent and usually benign clinical complication of
heparin therapy. However, some patients receiving heparin and heparin-based products …

Two decades of research into heparin‐induced thrombocytopenia (HIT) permit a personal
historical perspective on this fascinating syndrome. Previously, the frequency of HIT was …