The Role of Shear Stress in Coronary Artery Disease
Coronary artery disease is the leading cause of morbidity and mortality worldwide,
especially in developed countries, with an increasing incidence in developing countries …
especially in developed countries, with an increasing incidence in developing countries …
Shear stress, protein kinases and atherosclerosis
G Siasos, D Tousoulis, Z Siasou… - Current medicinal …, 2007 - ingentaconnect.com
Shear stress represents the frictional force that the flow of blood exerts at the endothelial
surface of the vessel wall and plays a central role in cell function and structure via managing …
surface of the vessel wall and plays a central role in cell function and structure via managing …
Role of endothelial shear stress in the natural history of coronary atherosclerosis and vascular remodeling: molecular, cellular, and vascular behavior
YS Chatzizisis, AU Coskun, M Jonas… - Journal of the American …, 2007 - jacc.org
Although the entire coronary tree is exposed to the atherogenic effect of the systemic risk
factors, atherosclerotic lesions form at specific arterial regions, where low and oscillatory …
factors, atherosclerotic lesions form at specific arterial regions, where low and oscillatory …
Role of biomechanical forces in the natural history of coronary atherosclerosis
Atherosclerosis remains a major cause of morbidity and mortality worldwide, and a thorough
understanding of the underlying pathophysiological mechanisms is crucial for the …
understanding of the underlying pathophysiological mechanisms is crucial for the …
Endothelial shear stress signal transduction and atherogenesis: from mechanisms to therapeutics
Atherosclerotic vascular disease and its complications are among the top causes of mortality
worldwide. In the vascular lumen, atherosclerotic plaques are not randomly distributed …
worldwide. In the vascular lumen, atherosclerotic plaques are not randomly distributed …
Hemodynamic shear stress and its role in atherosclerosis
Atherosclerosis, the leading cause of death in the developed world and nearly the leading
cause in the developing world, is associated with systemic risk factors including …
cause in the developing world, is associated with systemic risk factors including …
Wall shear stress and its role in atherosclerosis
M Zhou, Y Yu, R Chen, X Liu, Y Hu, Z Ma… - Frontiers in …, 2023 - frontiersin.org
Atherosclerosis (AS) is the major form of cardiovascular disease and the leading cause of
morbidity and mortality in countries around the world. Atherosclerosis combines the …
morbidity and mortality in countries around the world. Atherosclerosis combines the …
Shear stress and plaque development
SS Dhawan, RP Avati Nanjundappa… - Expert review of …, 2010 - Taylor & Francis
Although traditional cardiovascular risk factors 'prime the soil'for atherogenesis systemically,
atherosclerosis primarily occurs in a site-specific manner with a predilection towards the …
atherosclerosis primarily occurs in a site-specific manner with a predilection towards the …
How do we prevent the vulnerable atherosclerotic plaque from rupturing? Insights from in vivo assessments of plaque, vascular remodeling, and local endothelial …
I Andreou, AP Antoniadis, K Shishido… - Journal of …, 2015 - journals.sagepub.com
Coronary atherosclerosis progresses both as slow, gradual enlargement of focal plaque and
also as a more dynamic process with periodic abrupt changes in plaque geometry, size, and …
also as a more dynamic process with periodic abrupt changes in plaque geometry, size, and …
[HTML][HTML] The role of shear stress in the pathogenesis of atherosclerosis
KS Cunningham, AI Gotlieb - Laboratory investigation, 2005 - Elsevier
Although the pathobiology of atherosclerosis is a complex multifactorial process, blood flow-
induced shear stress has emerged as an essential feature of atherogenesis. This fluid drag …
induced shear stress has emerged as an essential feature of atherogenesis. This fluid drag …