[HTML][HTML] MUTYH is a potential prognostic biomarker and correlates with immune infiltrates in hepatocellular carcinoma

F Yang, Q Lian, B Ni, X Qiu, Y He, X Zou, F He, W Chen - Liver Research, 2022 - Elsevier
Background Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death
worldwide. The development of biomarkers for early detection and monitoring of HCC has …

[HTML][HTML] MUTYH: Not just polyposis

MC Curia, T Catalano, GM Aceto - World Journal of Clinical …, 2020 - ncbi.nlm.nih.gov
MUTYH is a base excision repair enzyme, it plays a crucial role in the correction of DNA
errors from guanine oxidation and may be considered a cell protective factor. In humans it is …

[HTML][HTML] Low MYH9 expression predicts a good prognosis for hepatocellular carcinoma

X Lin, GF Yu, S Zuo, RC Luo… - International Journal of …, 2018 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is currently one of the most common causes of cancer-
related death and one of the most commonly diagnosed cancers. MYH9 is thought to play a …

Reduced expression of MUTYH with suppressive activity against mutations caused by 8‐hydroxyguanine is a novel predictor of a poor prognosis in human gastric …

K Shinmura, M Goto, M Suzuki, H Tao… - The Journal of …, 2011 - Wiley Online Library
The MUTYH gene encodes a DNA glycosylase that can initiate the excision repair of
adenine mispaired with 8‐hydroxyguanine (8OHG) and is responsible for a susceptibility to …

High MutS homolog 2 expression predicts poor prognosis and is related to immune infiltration in endometrial carcinoma

X Lu, Y Ying, W Zhang, R Li… - Cell Biology …, 2023 - Wiley Online Library
Several studies have shown that MutS homolog 2 (MSH2) is highly expressed in many
cancer tissues. Transcriptome expression data were collected from the Cancer Genome …

Upregulated mH2A1 serves as an unfavorable prognostic indicator and promotes the progress of hepatocellular carcinoma (HCC)

G Yang, Y Yao, D Wu, H Guo, S Zhou, D Sun, X Guo… - Life Sciences, 2020 - Elsevier
Purpose To investigate the role and prognostic value of mH2A1 in the progression of
hepatocellular carcinoma (HCC). Methods Basing on the Cancer Genome Atlas-Liver …

[HTML][HTML] MutY-Homolog (MYH) inhibition reduces pancreatic cancer cell growth and increases chemosensitivity

G Sharbeen, J Youkhana, A Mawson, J McCarroll… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Patients with pancreatic ductal adenocarcinoma (PC) have a poor prognosis due to
metastases and chemoresistance. PC is characterized by extensive fibrosis, which creates a …

An intronic single nucleotide polymorphism in the MUTYH gene is associated with increased risk for HCV-induced hepatocellular carcinoma

A Sakurada, K Miyanishi, S Tanaka, M Sato… - Free Radical Biology …, 2018 - Elsevier
Background & aims The role of base excision repair genes in human hepatocarcinogenesis
has not yet been explored. Here, we investigated relationships between variants of these …

Expression of yhwaz and gene regulation network in hepatocellular carcinoma Erratum in/10.3892/ol. 2020.11996

Y Lin, L Sun, X Ye - Oncology Letters, 2020 - spandidos-publications.com
Abstract The adaptor protein 14-3-3ζ is encoded by the yhwaz gene and implicated in a
wide range of biological processes. In tumorigenesis, 14‑3‑3ζ recognizes specific …

Analysis of clinical significance and molecular characteristics of methionine metabolism and macrophage-related patterns in hepatocellular carcinoma based on …

D Wen, S Wang, J Yu, T Yu, Z Liu, Y Li - Cancer Biomarkers, 2024 - content.iospress.com
BACKGROUND: Increasing evidence has indicated that abnormal methionine metabolic
activity and tumour-associated macrophage infiltration are correlated with …