[HTML][HTML] Pretreatment with a combination of ligustrazine and berberine improves cardiac function in rats with coronary microembolization

Y Zhang, X Ma, C Guo, M Wang, N Kou, H Qu… - Acta pharmacologica …, 2016 - nature.com
Aim: We have shown that a combination of ligustrazine and berberine produces more
effective inhibition on platelet activation and inflammatory reactions in rat acute myocardial …

Ligustrazine attenuates myocardial injury induced by coronary microembolization in rats by activating the PI3K/Akt pathway

Q Su, X Lv, Z Ye - Oxidative Medicine and Cellular Longevity, 2019 - Wiley Online Library
Background/Aims. Coronary microembolization‐(CME‐) induced myocardial injury and
progressive cardiac dysfunction are mainly caused due to CME‐induced myocardial local …

Breviscapine pretreatment inhibits myocardial inflammation and apoptosis in rats after coronary microembolization by activating the PI3K/Akt/GSK-3β signaling …

ZQ Chen, Y Zhou, F Chen, JW Huang… - Drug design …, 2021 - Taylor & Francis
Purpose Coronary microembolization (CME) can cause myocardial inflammation, apoptosis
and progressive cardiac dysfunction. On the other hand, breviscapine exerts a significant …

Protective effect of glycyrrhizin on coronary microembolization‐induced myocardial dysfunction in rats

Y Yuan, B Li, W Peng, Z Xu - Pharmacology Research & …, 2021 - Wiley Online Library
Coronary microembolization (CME)‐induced inflammation and cardiomyocyte apoptosis are
two key factors contributing to CME‐induced myocardial dysfunction. High‐mobility group …

Cryptotanshinone ameliorates cardiac injury and cardiomyocyte apoptosis in rats with coronary microembolization

Y Zhang, F Luo, H Zhang, W He, T Liu… - Drug Development …, 2021 - Wiley Online Library
Coronary microembolization (CME) is a prevalent cardiovascular disease, especially
nowadays when percutaneous coronary intervention is widely applied. However, neither …

[HTML][HTML] Puerarin pretreatment attenuates cardiomyocyte apoptosis induced by coronary microembolization in rats by activating the PI3K/Akt/GSK-3β signaling …

ZQ Chen, Y Zhou, JW Huang, F Chen… - The Korean journal of …, 2021 - ncbi.nlm.nih.gov
Coronary microembolization (CME) is associated with cardiomyocyte apoptosis and cardiac
dysfunction. Puerarin confers protection against multiple cardiovascular diseases, but its …

Chinese herbal medicine Naoxintong capsule combined with dual antiplatelet therapy in a rat model of coronary microembolization induced by homologous …

MW Huang, H Wang, WJ Zhong, XY Wu… - Zhong xi yi jie he xue …, 2011 - europepmc.org
Objective In the present study, the efficacy of Naoxintong capsule (NXT), a compound
Chinese herbal medicine, combined with dual antiplatelet therapy (DA) in a rat model of …

Ligustrazine attenuates myocardial ischemia reperfusion injury in rats by activating the phosphatidylinositol 3-kinase/Akt pathway

L Lv, Q Meng, J Xu, J Gong, Y Cheng… - Annals of Clinical & …, 2012 - Assoc Clin Scientists
Materials and Methods Sprague-Dawley rats (n= 68, weighing 250–280g) were divided into
sham (n= 8), IR control (n= 10), 3 TMP pretreated (5, 10, 30mg/kg, n= 10, respectively) …

Resveratrol pretreatment inhibits myocardial apoptosis in rats following coronary microembolization via inducing the PI3K/Akt/GSK-3β signaling cascade

T Li, Z Chen, Y Zhou, H Li, J Xie, L Li - Drug Design, Development …, 2021 - Taylor & Francis
Purpose Coronary microembolization (CME) is associated with progressive cardiac
dysfunction, myocardial inflammation, and apoptosis. Resveratrol (RES) has a considerable …

[HTML][HTML] Effects of nicorandil on PI3K/Akt signaling pathway and its anti-apoptotic mechanisms in coronary microembolization in rats

Q Su, L Li, J Zhao, Y Sun, H Yang - Oncotarget, 2017 - ncbi.nlm.nih.gov
Coronary microembolization (CME) is a common complication of percutaneous coronary
intervention (PCI) for acute coronary syndrome. It leads to myocardial apoptosis and cardiac …