Protein MRI contrast agents as an effective approach for precision molecular imaging
Cancer and other acute and chronic diseases are results of perturbations of common
molecular determinants in key biological and signaling processes. Imaging is critical for …
molecular determinants in key biological and signaling processes. Imaging is critical for …
Precision detection of liver metastasis by collagen-targeted protein MRI contrast agent
The Liver is the most common organ for metastasis for various cancers, including uveal
melanoma, the most common primary intraocular tumor. Uveal melanoma metastasizes to …
melanoma, the most common primary intraocular tumor. Uveal melanoma metastasizes to …
Molecular MR contrast agents
Molecular magnetic resonance (MR) imaging utilizes molecular probes to provide added
biochemical or cellular information to what can already be achieved with anatomical and …
biochemical or cellular information to what can already be achieved with anatomical and …
Protein MRI contrast agent with unprecedented metal selectivity and sensitivity for liver cancer imaging
With available MRI techniques, primary and metastatic liver cancers that are associated with
high mortality rates and poor treatment responses are only diagnosed at late stages, due to …
high mortality rates and poor treatment responses are only diagnosed at late stages, due to …
Design of ProCAs (Protein‐Based Gd3+ MRI Contrast Agents) with High Dose Efficiency and Capability for Molecular Imaging of Cancer Biomarkers
Magnetic resonance imaging (MRI) is the leading imaging technique for disease
diagnostics, providing high resolution, three‐dimensional images noninvasively. MRI …
diagnostics, providing high resolution, three‐dimensional images noninvasively. MRI …
Molecular magnetic resonance contrast agents for the detection of cancer: past and present
A Bogdanov Jr, ML Mazzanti - Seminars in oncology, 2011 - Elsevier
Magnetic resonance imaging (MRI) is a powerful diagnostic tool with unsurpassed spatial
resolution that is capable of providing detailed information about the structure and …
resolution that is capable of providing detailed information about the structure and …
Design of a novel class of protein‐based magnetic resonance imaging contrast agents for the molecular imaging of cancer biomarkers
S Xue, J Qiao, F Pu, M Cameron… - Wiley Interdisciplinary …, 2013 - Wiley Online Library
Magnetic resonance imaging (MRI) of disease biomarkers, especially cancer biomarkers,
could potentially improve our understanding of the disease and drug activity during …
could potentially improve our understanding of the disease and drug activity during …
Quantitative molecular imaging with a single Gd-based contrast agent reveals specific tumor binding and retention in vivo
ML Johansen, Y Gao, MA Hutnick, SEL Craig… - Analytical …, 2017 - ACS Publications
Magnetic resonance imaging (MRI) has become an indispensable tool in the diagnosis and
treatment of many diseases, especially cancer. However, the poor sensitivity of MRI relative …
treatment of many diseases, especially cancer. However, the poor sensitivity of MRI relative …
Molecular imaging of extracellular matrix proteins with targeted probes using magnetic resonance imaging
M Salarian, OY Ibhagui, JJ Yang - … Reviews: Nanomedicine and …, 2020 - Wiley Online Library
The extracellular matrix (ECM) consists of proteins and carbohydrates that supports different
biological structures and processes such as tissue development, elasticity, and preservation …
biological structures and processes such as tissue development, elasticity, and preservation …
Targeted contrast agents for magnetic resonance molecular imaging of cancer
Conspectus Magnetic resonance imaging (MRI) is a clinical imaging modality that provides
high-resolution images of soft tissues, including cancerous lesions. Stable gadolinium (III) …
high-resolution images of soft tissues, including cancerous lesions. Stable gadolinium (III) …
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