[HTML][HTML] Maintenance antiretroviral therapies in HIV-infected subjects with undetectable plasma HIV RNA after triple-drug therapy

DV Havlir, IC Marschner, MS Hirsch… - … England Journal of …, 1998 - Mass Medical Soc
Background Combination antiretroviral therapy with indinavir, zidovudine, and lamivudine
can suppress the level of human immunodeficiency virus (HIV) RNA in plasma below the …

[HTML][HTML] A randomized trial of three maintenance regimens given after three months of induction therapy with zidovudine, lamivudine, and indinavir in previously …

G Pialoux, F Raffi, F Brun-Vezinet… - … England Journal of …, 1998 - Mass Medical Soc
Background The long-term effectiveness of potent three-drug antiretroviral regimens for the
treatment of human immunodeficiency virus type 1 (HIV-1) infection is limited by problems …

Predictors of Virologic and Clinical Outcomes in HIV-1–Infected Patients Receiving Concurrent Treatment with Indinavir, Zidovudine, and Lamivudine: AIDS Clinical …

LM Demeter, MD Hughes, RW Coombs… - Annals of internal …, 2001 - acpjournals.org
Background: A substantial proportion of patients with HIV infection will not respond to
antiretroviral therapy. Early predictors of response to treatment are needed to identify …

[HTML][HTML] Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy

RM Gulick, JW Mellors, D Havlir, JJ Eron… - … England Journal of …, 1997 - Mass Medical Soc
Background The new protease inhibitors are potent inhibitors of the human
immunodeficiency virus (HIV), and in combination with other antiretroviral drugs they may be …

Mechanisms of virologic failure in previously untreated HIV-infected patients from a trial of induction-maintenance therapy

D Descamps, P Flandre, V Calvez, G Peytavin… - Jama, 2000 - jamanetwork.com
ContextIn the Trilège trial, following induction with a zidovudine, lamivudine, and indinavir
regimen, human immunodeficiency virus (HIV) replication was less suppressed by 2-drug …

Simultaneous vs sequential initiation of therapy with indinavir, zidovudine, and lamivudine for HIV-1 infection: 100-week follow-up

RM Gulick, JW Mellors, D Havlir, JJ Eron, C Gonzalez… - Jama, 1998 - jamanetwork.com
Context.—Combination antiretroviral therapy can markedly suppress human
immunodeficiency virus (HIV) replication but the duration of HIV suppression varies among …

Reduction of HIV-1 in blood and lymph nodes following potent antiretroviral therapy and the virologic correlates of treatment failure

JK Wong, HF Günthard, DV Havlir… - Proceedings of the …, 1997 - National Acad Sciences
Potent antiretroviral therapy can reduce plasma HIV RNA levels below the threshold of
detection for periods of a year or more. The magnitude of HIV RNA reduction in the lymphoid …

Six-year follow-up of HIV-1-infected adults in a clinical trial of antiretroviral therapy with indinavir, zidovudine, and lamivudine

RM Gulick, A Meibohm, D Havlir, JJ Eron, A Mosley… - Aids, 2003 - journals.lww.com
Objective: To assess virological and immunological responses and toxicity in subjects
receiving combination antiretroviral therapy. Design: Six-year follow-up of a single arm of a …

[HTML][HTML] Virologic and immunologic consequences of discontinuing combination antiretroviral-drug therapy in HIV-infected patients with detectable viremia

SG Deeks, T Wrin, T Liegler, R Hoh… - … England Journal of …, 2001 - Mass Medical Soc
Background In many patients with human immunodeficiency virus (HIV) infection, therapy
with potent antiretroviral drugs does not result in complete suppression of HIV replication …

Virological and immunological responses to a once-a-day antiretroviral regimen with didanosine, lamivudine and efavirenz

F Maggiolo, M Migliorino, R Maserati, A Pan… - Antiviral …, 2002 - journals.sagepub.com
Current antiretroviral drugs cannot eradicate HIV infections, and persons living with HIV are
often faced with very demanding daily therapeutic schedules that can induce poor …