Hydrogel-coated microneedle arrays for minimally invasive sampling and sensing of specific circulating nucleic acids from skin interstitial fluid

D Al Sulaiman, JYH Chang, NR Bennett, H Topouzi… - ACS …, 2019 - ACS Publications
Minimally invasive technologies that can sample and detect cell-free nucleic acid
biomarkers from liquid biopsies have recently emerged as clinically useful for early …

Microneedle array encapsulated with programmed DNA hydrogels for rapidly sampling and sensitively sensing of specific microRNA in dermal interstitial fluid

Q Yang, Y Wang, T Liu, C Wu, J Li, J Cheng, W Wei… - ACS …, 2022 - ACS Publications
Author: Please verify that the changes made to improve the English still retain your original
meaning. Detection of microRNA (miRNA) in dermal interstitial fluid (ISF) has emerged as …

Hydrogel microneedle-assisted assay integrating aptamer probes and fluorescence detection for reagentless biomarker quantification

H Zheng, A GhavamiNejad, P GhavamiNejad… - ACS …, 2022 - ACS Publications
Analyzing interstitial fluid (ISF) via microneedle (MN) devices enables patient health
monitoring in a minimally invasive manner and in point-of-care settings. However, most MN …

Interstitial fluid biomarkers' minimally invasive monitoring using microneedle sensor arrays

J Li, H Lu, Y Wang, S Yang, Y Zhang, W Wei… - Analytical …, 2021 - ACS Publications
Skin interstitial fluid (ISF) is a biofluid with information-rich biomarkers for disease diagnosis
and prognosis. Microneedle (MN) integration of sampling and instant biomarker readout …

Superswelling microneedle arrays for dermal interstitial fluid (prote) omics

E Laszlo, G De Crescenzo… - Advanced Functional …, 2021 - Wiley Online Library
The noninvasive sampling of dermal interstitial fluid (ISF) for the monitoring of clinical
biomarkers is a greatly appealing area of research. The identification of molecular …

A sample and detection microneedle patch for psoriasis MicroRNA biomarker analysis in interstitial fluid

Y Qiao, J Du, R Ge, H Lu, C Wu, J Li, S Yang… - Analytical …, 2022 - ACS Publications
Skin interstitial fluid (ISF) containing a great variety of molecular biomarkers derived from
cells and subcutaneous blood capillaries has recently emerged as a clinically potential …

Wearable microneedle array-based sensor for transdermal monitoring of pH levels in interstitial fluid

M Dervisevic, E Dervisevic, L Esser, CD Easton… - Biosensors and …, 2023 - Elsevier
Microneedle-based wearable sensors offer an alternative approach to traditional invasive
blood-based health monitoring and disease diagnostics techniques. Instead of blood …

Engineered microneedles for interstitial fluid cell‐free DNA capture and sensing using iontophoretic dual‐extraction wearable patch

B Yang, X Fang, J Kong - Advanced Functional Materials, 2020 - Wiley Online Library
Interstitial fluid (ISF), as an emerging source of biomarkers, is unmistakably significant for
disease diagnosis. Microneedles (MNs) provide a minimally invasive approach for extracting …

3D printed hydrogel microneedle arrays for interstitial fluid biomarker extraction and colorimetric detection

M Razzaghi, A Seyfoori, E Pagan, E Askari… - Polymers, 2023 - mdpi.com
To treat and manage chronic diseases, it is necessary to continuously monitor relevant
biomarkers and modify treatment as the disease state changes. Compared to other bodily …

An integrated wearable microneedle array for the continuous monitoring of multiple biomarkers in interstitial fluid

F Tehrani, H Teymourian, B Wuerstle… - Nature Biomedical …, 2022 - nature.com
Implementations of wearable microneedle-based arrays of sensors for the monitoring of
multiple biomarkers in interstitial fluid have lacked system integration and evidence of robust …