Spectral editing allows direct measurement of low-concentration metabolites, such as GABA,
glutathione (GSH) and lactate (Lac), relevant for understanding brain (patho) physiology …

Edited MRS allows the detection of low-concentration metabolites, whose signals are not
resolved in the MR spectrum. Tailored acquisitions can be designed to detect, for example …

Magnetic resonance spectroscopy (MRS) is the only biomedical imaging method that can
noninvasively detect endogenous signals from the neurotransmitter γ-aminobutyric acid …

GABA levels can be measured using proton MRS with a two‐step editing sequence.
However due to the low concentration of GABA, long acquisition time is usually needed to …

Purpose Detection of endogenous metabolites using multiplexed editing substantially
improves the efficiency of edited magnetic resonance spectroscopy. Multiplexed editing (ie …

The Proton magnetic resonance (1H‐MRS) spectrum contains information about the
concentration of tissue metabolites within a predefined region of interest (a voxel). The …

Purpose To evaluate the feasibility of simultaneous MR spectroscopic imaging (MRSI) of
gamma‐aminobutyric acid (GABA) and glutathione (GSH) in the human brain using …

Purpose The most common γ‐aminobutyric‐acid (GABA) editing approach, MEGA‐PRESS,
uses J‐editing to measure GABA distinct from larger overlapping metabolites, but suffers …

Purpose To investigate the quantitative impact of frequency drift on Gamma‐Aminobutyric
acid (GABA+)‐edited MRS of the human brain at 3 Tesla (T). Methods Three sequential …

Purpose The purpose of this study is to describe the Gannet toolkit for the quantitative batch
analysis of gamma‐aminobutyric acid (GABA)‐edited MRS data. Materials and Methods …