Translational efficiency across healthy and tumor tissues is proliferation‐related | Molecular
Systems Biology All EMBO Press journals Open Access as of 1 January 2024 - read the FAQs …

Translation is a process during which proteins are synthesized form mRNAs via highly
coordinated actions of transfer RNAs (tRNAs), ribosomes and a large number of auxiliary …

After cells divide, the new cells have to synthesize all the necessary cellular components in
time for the next division. There is a lower bound of time required for cells to double their …

Translation and its regulation in cancer biology and medicine Page 2 Translation and Its
Regulation in Cancer Biology and Medicine Page 3 Armen Parsyan Editor Translation and Its …

All processes associated with cellular function are likely to contribute to disease. Particularly
in the cancer field, most major therapeutic innovations have originated from the elucidation …

Highlights•Activation of oncogenes co-regulates translation and metabolism.•Findings
suggest translational control of metabolism.•Functional studies reveal that metabolism …

Recent work has brought to light many different mechanisms of translation initiation that
function in cells in parallel to canonical cap‐dependent initiation. This has important …

Tumor tissues are constituted by a dynamic diversity of malignant and non-malignant cells,
which shape a puzzling biological ecosystem affecting cancer biology and response to …

Translation of mRNA s into proteins is a key cellular process. Ribosome binding sites and
stop codons provide signals to initiate and terminate translation, while stable secondary …

Science progresses by an iterative process whereby discoveries build upon a foundation of
established facts and principles. The integrity of the advancement of knowledge depends …