Chronic inflammation: a common and important factor in the pathogenesis of neoplasia

D Schottenfeld, J Beebe‐Dimmer - CA: a cancer journal for …, 2006 - Wiley Online Library
A causal link between chronic inflammation and carcinogenesis is explored by reviewing
illustrative examples of specific cancers and causal agents and mechanisms. The causal …

Chronic inflammation and cancer.

E Shacter, SA Weitzman - Oncology (Williston Park, NY), 2002 - europepmc.org
A substantial body of evidence supports the conclusion that chronic inflammation can
predispose an individual to cancer, as demonstrated by the association between chronic …

Mechanisms of disease: inflammation and the origins of cancer

SF Moss, MJ Blaser - Nature clinical practice Oncology, 2005 - nature.com
Many common cancers develop as a consequence of years of chronic inflammation.
Increasing evidence indicates that the inflammation may result from persistent mucosal or …

Inflammation and cancer: an epidemiological perspective

MJ Thun, SJ Henley, T Gansler - Cancer and Inflammation …, 2004 - Wiley Online Library
Many chronic inflammatory conditions increase the risk of cancer in affected tissues. Clinical
conditions that involve both inflammation and increased cancer risk include a broad range of …

Inflammation in the genesis and perpetuation of cancer: summary and recommendations from a national cancer institute–sponsored meeting

RM Peek Jr, S Mohla, RN DuBois - 2005 - AACR
Abstract The Inflammation and Cancer Think Tank Meeting was organized by the National
Cancer Institute with the purpose of identifying research advances, gaps, and opportunities …

Inflammation and cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation

SH Itzkowitz, X Yio - American journal of physiology …, 2004 - journals.physiology.org
Patients with ulcerative colitis and Crohn's disease are at increased risk for developing
colorectal cancer. To date, no known genetic basis has been identified to explain colorectal …

Identifying and defusing weapons of mass inflammation in carcinogenesis

LJ Hofseth, L Ying - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2006 - Elsevier
The continued cancer risks associated with chronic inflammation necessitate the
identification of inflammatory molecules and the cancer pathways they affect. Evidence …

Pathways connecting inflammation and cancer

P Allavena, C Garlanda, MG Borrello, A Sica… - Current opinion in …, 2008 - Elsevier
Chronic and persistent inflammation contributes to cancer development and can predispose
to carcinogenesis. Infection-driven inflammations are involved in the pathogenesis of …

The dual role of inflammation in colon carcinogenesis

G Monteleone, F Pallone, C Stolfi - International Journal of Molecular …, 2012 - mdpi.com
Chronic inflammation characterizing patients with inflammatory bowel disease (IBD)
represents a major risk factor for the development of colorectal cancer. Mechanisms …

Inflammation and colon cancer

J Terzić, S Grivennikov, E Karin, M Karin - Gastroenterology, 2010 - Elsevier
The connection between inflammation and tumorigenesis is well-established and in the last
decade has received a great deal of supporting evidence from genetic, pharmacological …