Background: Autophagy, as an indispensable metabolism, plays pivotal roles in maintaining
intracellular homeostasis. Nutritional stress, amino acid deficiency, oxidative stress, and …

Both acute kidney injury (AKI) and chronic kidney disease (CKD) that lead to diminished
kidney function are interdependent risk factors for increased mortality. If untreated over time …

Reactive oxygen species (ROS) are highly reactive signaling molecules that maintain redox
homeostasis in mammalian cells. Dysregulation of redox homeostasis under pathological …

Significance: Autophagy is emerging as an important pathway in many biological processes
and diseases. This review summarizes the current progress on the role of autophagy in …

Autophagy is a ubiquitous intracellular cytoprotective quality control program that maintains
cellular homeostasis by recycling superfluous cytoplasmic components (lipid droplets …

Autophagy is a highly conserved process that degrades cellular long-lived proteins and
organelles. Accumulating evidence indicates that autophagy plays a critical role in kidney …

Autophagy is a conserved multistep pathway that degrades and recycles damaged
organelles and macromolecules to maintain intracellular homeostasis. The autophagy …

Abstract Purpose of Review Autophagy promotes cellular health in response to various
cellular stresses and to changes in nutrient conditions. In this review, we focus on the role of …

Inflammation plays a pivotal role in pathophysiological processes of kidney diseases.
Macroautophagy/autophagy plays multiple roles in inflammatory responses, and the …

Diabetic kidney disease, a leading cause of end-stage renal disease, has become a serious
public health problem worldwide and lacks effective therapies. Autophagy is a highly …