[HTML][HTML] Helicobacter pylori CagA: From Pathogenic Mechanisms to Its Use as an Anti-Cancer Vaccine

M Stein, P Ruggiero, R Rappuoli, F Bagnoli - Frontiers in immunology, 2013 - frontiersin.org
Helicobacter pylori colonizes the gastric mucosa of more than 50% of the human population,
causing chronic inflammation, which however is largely asymptomatic. Nevertheless, H …

[HTML][HTML] Pathogenicity of Helicobacter pylori in cancer development and impacts of vaccination

H Maleki Kakelar, A Barzegari, J Dehghani, S Hanifian… - Gastric Cancer, 2019 - Springer
Helicobacter pylori affect around 50% of the population worldwide. More importantly, the
gastric infection induced by this bacterium is deemed to be associated with the progression …

Helicobacter pylori and its effect on innate and adaptive immunity: new insights and vaccination strategies

M Sundquist, M Quiding-Järbrink - Expert Review of …, 2010 - Taylor & Francis
Infection with the gastric bacterium Helicobacter pylori invariably leads to active chronic
gastritis, and is strongly correlated to peptic ulcer disease, gastric adenocarcinoma and …

Vaccination against Helicobacter pylori–An approach for cancer prevention?

V Friedrich, M Gerhard - Molecular Aspects of Medicine, 2023 - Elsevier
The gram-negative bacterium Helicobacter pylori is the most common chronic bacterial
infection and the main cause of gastric cancer. Due to the increasing antimicrobial …

Why can't we make an effective vaccine against Helicobacter pylori?

P Sutton, YT Chionh - Expert review of vaccines, 2013 - Taylor & Francis
Helicobacter pylori is a major human pathogen that colonizes the stomach and is the lead
etiological agent for several pathologies. An effective vaccine against these bacteria would …

Helicobacter pylori Infection, Oncogenic Pathways and Epigenetic Mechanisms in Gastric Carcinogenesis

SZ Ding, JB Goldberg, M Hatakeyama - Future oncology, 2010 - Taylor & Francis
Chronic colonization of the human stomach by Helicobacter pylori, a Gram-negative
bacterium, is the major cause of chronic gastritis, peptic ulcers and gastric cancer. Recent …

The Current Status of Helicobacter pylori Vaccines: A Review

S Kabir - Helicobacter, 2007 - Wiley Online Library
Helicobacter pylori, a Gram‐negative flagellate bacterium that infects the stomach of more
than half of the global population, is regarded as the leading cause of chronic gastritis …

Helicobacter pylori vaccines spiral into the new millennium

P Sutton, C Doidge - Digestive and liver disease, 2003 - Elsevier
This article reviews the current situation regarding research towards an effective human
vaccine against Helicobacter pylori, with particular emphasis on developments in the new …

Progress in vaccine development against Helicobacter pylori

AM Svennerholm, A Lundgren - FEMS Immunology & Medical …, 2007 - academic.oup.com
Based on the very high prevalence of diseases caused by Helicobacter pylori, particularly in
the developing world, and the rapid emergence of antibiotic resistance among clinical …

[HTML][HTML] Helicobacter pylori CagA and gastric cancer: a paradigm for hit-and-run carcinogenesis

M Hatakeyama - Cell host & microbe, 2014 - cell.com
Helicobacter pylori is a gastric bacterial pathogen that is etiologically linked to human gastric
cancer. The cytotoxin-associated gene A (CagA) protein of H. pylori, which is delivered into …