Renal anaemia and EPO hyporesponsiveness associated with vitamin D deficiency: the potential role of inflammation

A Icardi, E Paoletti, L De Nicola… - Nephrology Dialysis …, 2013 - academic.oup.com
Resistance to erythropoiesis-stimulating agents (ESAs) has been observed in a
considerable proportion of patients with chronic kidney disease (CKD) and it is reportedly …

Serum 25 (OH)-cholecalciferol concentration is associated with hemoglobin level and erythropoietin resistance in patients on maintenance hemodialysis

Z Kiss, C Ambrus, C Almasi, K Berta, G Deák… - Nephron Clinical …, 2011 - karger.com
Background: Resistance to erythropoiesis-stimulating agents (ESAs) has been observed in
patients with chronic kidney disease (CKD) and it is associated with clinical outcomes. The …

Vitamin D and immune function in chronic kidney disease

WC Liu, CM Zheng, CL Lu, YF Lin, JF Shyu, CC Wu… - Clinica chimica acta, 2015 - Elsevier
The common causes of death in chronic kidney disease (CKD) patients are cardiovascular
events and infectious disease. These patients are also predisposed to the development of …

Anaemia and inflammation: what are the implications for the nephrologist?

P Stenvinkel - Nephrology Dialysis Transplantation, 2003 - academic.oup.com
End-stage renal disease (ESRD) is characterized by a high mortality rate, which is mainly
caused by cardiovascular disease. In patients with ESRD, high levels of pro-inflammatory …

Vitamin D insufficiency: implications for the immune system

F Baeke, C Gysemans, H Korf, C Mathieu - Pediatric nephrology, 2010 - Springer
Chronic kidney disease (CKD) is characterized by a loss of kidney function and
dysregulation of vitamin D metabolism. Well known are the defects in final activation of …

New insights on the role of vitamin D in the progression of renal damage

S Lucisano, M Buemi, A Passantino, C Aloisi… - Kidney and Blood …, 2013 - karger.com
Several studies indicate a relationship between hypovitaminosis D, survival, vascular
calcification and inflammation. In addition to its central role in the regulation of bone mineral …

Effect of intravenous ascorbic acid in hemodialysis patients with EPO-hyporesponsive anemia and hyperferritinemia

N Attallah, Y Osman-Malik, S Frinak… - American journal of kidney …, 2006 - Elsevier
Background: Although erythropoietin (EPO)-hyporesponsive anemia in hemodialysis
patients most commonly results from iron deficiency, the contributory role of chronic …

Nutritional-inflammation status and resistance to erythropoietin therapy in haemodialysis patients

F Locatelli, S Andrulli, B Memoli, C Maffei… - Nephrology Dialysis …, 2006 - academic.oup.com
Background. Chronic kidney disease patients who are resistant to erythropoietin (EPO)
treatment may suffer from malnutrition and/or inflammation. Methods. In a cross-sectional …

The immunoregulatory function of vitamin D: implications in chronic kidney disease

KA Sterling, P Eftekhari, M Girndt, PL Kimmel… - Nature Reviews …, 2012 - nature.com
Cardiovascular and infectious diseases remain the most common causes of death among
patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD). Basic …

Acute-phase response predicts erythropoietin resistance in hemodialysis and peritoneal dialysis patients

J Gunnell, JY Yeun, TA Depner, GA Kaysen - American journal of kidney …, 1999 - Elsevier
We defined erythropoietin (EPO) resistance by the ratio of the weekly EPO dose to
hematocrit (Hct), yielding a continuously distributed variable (EPO/Hct). EPO resistance is …