Cutaneous squamous cell carcinoma (cSCC) ranks second in the frequency of all skin
cancers. The balance between keratinocyte proliferation and differentiation is disrupted in …

Epidermal homeostasis depends on the coordinated control of keratinocyte cell cycle.
Differentiation and the alteration of this balance can result in neoplastic development. Here …

Genetic studies have revealed a critical role of the distal-less homeobox gene 5 (Dlx5) in the
pathogenesis of ovarian cancer, lung cancer, and T-cell lymphoma; however, the role and …

Epidermal homeostasis relies on a well-defined transcriptional control of keratinocyte
proliferation and differentiation, which is critical to prevent skin diseases such as atopic …

Objective Distal‐less homeobox 6 (DLX6) has been reported to play important roles in the
development of craniofacial structures, inner ear, limb, and brain. We found in our previous …

Well-regulated epidermal homeostasis depends on the function of different classes of
factors, such as transcription regulators and receptors. Alterations in this homeostatic …

The distal-less homeobox gene (dlx) 5 encodes a transcription factor that controls jaw
formation and appendage differentiation during embryonic development. We had previously …

Background The DLX gene family encodes for homeobox transcription factors involved in
the control of morphogenesis and tissue homeostasis. Their expression can be regulated by …

The human DLX homeobox genes, which are related to Dll (Drosophila distal-less gene),
encode transcription factors that are expressed primarily in embryonic development …

Long noncoding RNAs (lncRNAs) are involved in multiple functions such as the regulation of
cellular homeostasis. They play prominent roles in the pathogenesis of human cancer, and …