BACKGROUND In vitro follicle growth is a promising fertility preservation strategy in which
ovarian follicles are cultured to produce mature and fertilization-competent oocytes …

Purpose In vitro follicle growth (IVFG) is an investigational fertility preservation technique in
which immature follicles are grown in culture to produce mature eggs that can ultimately be …

The growth and maturation of oocytes in vitro from the earliest primordial follicle stage is a
major technical challenge for reproductive science that, if overcome, will have many …

The factors and processes involved in primate follicular development are complex and not
fully understood. An encapsulated three-dimensional (3D) follicle culture system could be a …

The removal and cryostorage of ovarian cortical biopsies is now offered as a fertility
preservation option for young women. The only available option to restore fertility using this …

Tissue banking of ovarian material is being increasingly offered to a variety of patients as a
means of fertility preservation. This tissue comprises thin cortical surface biopsies that …

The development of technologies to grow oocytes from the most abundant primordial
follicles to maturity in vitro holds many attractions for clinical practice, animal production …

The exact mechanisms regulating in vivo folliculogenesis in mammalians have only been
partly unravelled. Some processes, such as the initiation of growth of primordial follicles are …

OBJECTIVE:: To develop an efficient isolation technique for human primordial follicles.
DESIGN:: Prospective, experimental study of ovarian biopsies collected from healthy women …

Mature oocytes are rare and precious cells. A technology which generates larger numbers
would be very welcome in clinical practice, animal production technology and research …