Cerebral Plasmodium falciparum malaria: The role of PfEMP1 in its pathogenesis and immunity, and PfEMP1‐based vaccines to prevent it
Malaria, a mosquito‐borne infectious disease caused by parasites of the genus Plasmodium
continues to be a major health problem worldwide. The unicellular Plasmodium‐parasites …
continues to be a major health problem worldwide. The unicellular Plasmodium‐parasites …
The role of PfEMP1 as targets of naturally acquired immunity to childhood malaria: prospects for a vaccine
PC Bull, AI Abdi - Parasitology, 2016 - cambridge.org
The Plasmodium falciparum erythrocyte membrane protein 1 antigens that are inserted onto
the surface of P. falciparum infected erythrocytes play a key role both in the pathology of …
the surface of P. falciparum infected erythrocytes play a key role both in the pathology of …
PfEMP1: an antigen that plays a key role in the pathogenicity and immune evasion of the malaria parasite Plasmodium falciparum
ND Pasternak, R Dzikowski - The international journal of biochemistry & …, 2009 - Elsevier
The deadliest form of human malaria is caused by the protozoan parasite Plasmodium
falciparum affecting millions worldwide every year. P. falciparum virulence is attributed to its …
falciparum affecting millions worldwide every year. P. falciparum virulence is attributed to its …
PfEMP1–a parasite protein family of key importance in Plasmodium falciparum malaria immunity and pathogenesis
L Hviid, ATR Jensen - Advances in parasitology, 2015 - Elsevier
Plasmodium falciparum causes the most severe form of malaria and is responsible for
essentially all malaria-related deaths. The accumulation in various tissues of erythrocytes …
essentially all malaria-related deaths. The accumulation in various tissues of erythrocytes …
[HTML][HTML] Surface antigens of Plasmodium falciparum-infected erythrocytes as immune targets and malaria vaccine candidates
Understanding the targets and mechanisms of human immunity to malaria caused by
Plasmodium falciparum is crucial for advancing effective vaccines and developing tools for …
Plasmodium falciparum is crucial for advancing effective vaccines and developing tools for …
[HTML][HTML] Targets of antibodies against Plasmodium falciparum–infected erythrocytes in malaria immunity
Plasmodium falciparum is the major cause of malaria globally and is transmitted by
mosquitoes. During parasitic development, P. falciparum–infected erythrocytes (P …
mosquitoes. During parasitic development, P. falciparum–infected erythrocytes (P …
Cloning the P. falciparum gene encoding PfEMP1, a malarial variant antigen and adherence receptor on the surface of parasitized human erythrocytes
DI Baruch, BL Pasloske, HB Singh, X Bi, XC Ma… - Cell, 1995 - cell.com
Plasmodium falciparum-infected human erythrocytes evade host immunity by expression of
a ceil-surface variant antigen and receptors for adherence to endothelial cells. These …
a ceil-surface variant antigen and receptors for adherence to endothelial cells. These …
Sequential, ordered acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 domains
The binding of erythrocytes infected with mature blood stage parasites to the vascular bed is
key to the pathogenesis of malignant malaria. The binding is mediated by members of …
key to the pathogenesis of malignant malaria. The binding is mediated by members of …
Evasion of immunity to Plasmodium falciparum malaria by IgM masking of protective IgG epitopes in infected erythrocyte surface-exposed PfEMP1
L Barfod, MB Dalgaard, ST Pleman… - Proceedings of the …, 2011 - National Acad Sciences
Plasmodium falciparum malaria is a major cause of mortality and severe morbidity. Its
virulence is related to the parasite's ability to evade host immunity through clonal antigenic …
virulence is related to the parasite's ability to evade host immunity through clonal antigenic …
Antibodies to variant antigens on the surfaces of infected erythrocytes are associated with protection from malaria in Ghanaian children
D Dodoo, T Staalsoe, H Giha, JAL Kurtzhals… - Infection and …, 2001 - Am Soc Microbiol
Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is a variant antigen
expressed on the surface of infected erythrocytes. Each parasite genome contains about 40 …
expressed on the surface of infected erythrocytes. Each parasite genome contains about 40 …