Cardiac fibrosis is a common pathological manifestation in multiple cardiovascular diseases
and often results in myocardial stiffness and cardiac dysfunctions. LncRNA (long noncoding …

Cardiac fibrosis is characterized by the activation of cardiac fibroblasts and accumulation of
extracellular matrix. METTL3, a component of methyltransferase complex, participates in …

Cardiac fibrosis, a common pathology in inherited and acquired heart diseases,
necessitates the identification of diagnostic and therapeutic targets. Methyltransferase Like 1 …

Background Cardiac fibrosis following myocardial infarction (MI) leads to cardiac remodeling
and dysfunction. Dysregulation of Smad7 which negatively regulates the profibrotic …

Myocardial fibrosis (MF) is a reactive remodeling process in response to myocardial injury. It
is mainly manifested by the proliferation of cardiac muscle fibroblasts and secreting …

Long-chain noncoding RNA (lncRNA) is a new class of molecular regulators in heart
development and disease. However, the role of specific lncRNA in cardiac fibrosis remains …

Rationale: Cardiac fibroblasts (CFs) drive extracellular matrix remodeling after pressure
overload, leading to fibrosis and diastolic dysfunction. Recent studies described the role of …

Cardiac fibrosis remains an unresolved problem in heart disease. Its etiology is directly
caused by the activation and proliferation of cardiac fibroblasts (CFs). However, there is …

Cardiac fibrosis is known as the expansion of the cardiac interstitium through excessive
deposition of extracellular matrix proteins; this process is performed by a multifunctional cell …

Cardiac fibrosis is a pathological process underlying myocardial remodeling and is
characterized by excessive deposition of the myocardial extracellular matrix. Long …