Knee osteoarthritis (OA) is a degenerative knee joint disease that results from the
breakdown of joint cartilage and underlying bone, affecting about 3.3% of the world's …

Introduction Osteoarthritis (OA) is a common disease worldwide leading to significant
morbidity. The underlying disease process is multifactorial however there is increasing focus …

Since microRNA was discovered in the late 1990s the role of non-coding RNAs in the
regulation of cellular processes has been confirmed. Intensive researches have revealed a …

Objective To use deep sequencing to identify novel microRNAs (miRNAs) in human
osteoarthritic cartilage which have a functional role in chondrocyte phenotype or function …

The etiology of osteoarthritis (OA) is complex, with genetic, developmental, biochemical, and
biomechanical factors contributing to the disease process. Chondrocytes in articular …

Osteoarthritis (OS) is the most frequent degenerative condition in the joints, disabling many
adults. Several abnormalities in the articular cartilage, subchondral bone, synovial tissue …

Osteoarthritis (OA) is the most prevalent degenerative joint disease and is accompanied by
pain and joint dysfunction. Its clinical treatment tends to be unsatisfactory. Novel targets in …

Background Osteoarthritis (OA) is the most orthopedic condition. The pattern of gene
expression and the transcription factors that exert control of chondrogenesis have been …

MicroRNAs are small double-stranded RNAs, which negatively regulate gene expression
and have been shown to have key roles in both chondrocyte development and cartilage …

Background: Osteoarthritis (OA) is the most common chronic joint disease and it may
progressively cause disability and compromise quality of life. Lately, the role of miRNAs in …