[HTML][HTML] Western diet as a trigger of Alzheimer's disease: From metabolic syndrome and systemic inflammation to neuroinflammation and neurodegeneration

A Więckowska-Gacek, A Mietelska-Porowska… - Ageing research …, 2021 - Elsevier
An excess of saturated fatty acids and simple sugars in the diet is a known environmental
risk factor of Alzheimer's disease (AD) but the holistic view of the interacting processes …

[HTML][HTML] Western diet induces impairment of liver-brain Axis Accelerating neuroinflammation and amyloid pathology in Alzheimer's disease

A Wiȩckowska-Gacek… - Frontiers in aging …, 2021 - frontiersin.org
Alzheimer's disease (AD) is an aging-dependent, irreversible neurodegenerative disorder
and the most common cause of dementia. The prevailing AD hypothesis points to the central …

[HTML][HTML] Blood-brain barrier disruption: mechanistic links between Western diet consumption and dementia

TM Hsu, SE Kanoski - Frontiers in aging neuroscience, 2014 - frontiersin.org
Both obesity and Alzheimer's disease (AD) are major health burdens in Western societies.
While commonly viewed as having separate etiologies, this review highlights data …

Shared neuropathological characteristics of obesity, type 2 diabetes and Alzheimer's disease: impacts on cognitive decline

JM Walker, FE Harrison - Nutrients, 2015 - mdpi.com
In the past few decades, the prevalence of obesity and type 2 diabetes mellitus (T2DM), as
well as older individuals at risk for Alzheimer's disease (AD), has increased. While the …

[HTML][HTML] Dietary regulation of gut-brain axis in Alzheimer's disease: Importance of microbiota metabolites

DM Frausto, CB Forsyth, A Keshavarzian… - Frontiers in …, 2021 - frontiersin.org
Alzheimer's disease (AD) is a neurodegenerative disease that impacts 45 million people
worldwide and is ranked as the 6th top cause of death among all adults by the Centers for …

Diet and inflammation in cognitive ageing and Alzheimer's disease

AM McGrattan, B McGuinness, MC McKinley… - Current nutrition …, 2019 - Springer
Abstract Purpose of Review Nutrition is known to modulate the immune system and may
alter neuroinflammatory processes implicated in the pathogenesis of Alzheimer's disease …

Dietary patterns and Alzheimer's disease: An updated review linking nutrition to neuroscience

I Ellouze, J Sheffler, R Nagpal, B Arjmandi - Nutrients, 2023 - mdpi.com
Alzheimer's disease (AD) is a growing concern for the aging population worldwide. With no
current cure or reliable treatments available for AD, prevention is an important and growing …

Diet and Alzheimer's dementia–Nutritional approach to modulate inflammation

K Szczechowiak, BS Diniz, J Leszek - Pharmacology Biochemistry and …, 2019 - Elsevier
Background Alzheimer's disease (AD) is the most common neurodegenerative disease
causing dementia in the elderly population. Due to the fact that there is still no cure for …

[HTML][HTML] Diet-microbiota-brain axis in Alzheimer's disease

HJ Kincaid, R Nagpal, H Yadav - Annals of nutrition and metabolism, 2021 - karger.com
Background: Alzheimer's disease (AD) is the most common form of dementia, particularly in
older adults, with clinical manifestations of progressive cognitive decline and functional …

Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse model of Alzheimer's disease

LC Graham, JM Harder, I Soto, WN De Vries… - Scientific reports, 2016 - nature.com
Studies have assessed individual components of a western diet, but no study has assessed
the long-term, cumulative effects of a western diet on aging and Alzheimer's disease (AD) …