Smokers have a significantly higher risk for developing coronary and cerebrovascular
disease than nonsmokers. Advanced glycation end products (AGEs) are reactive, cross …

The incidence of certain ageing sequelae such as lung and cardiovascular disease and
cataract are higher in smokers than in non-smokers. We recently proposed that certain …

Abstract Background Advanced glycation endproducts (AGEs) arise from the spontaneous
reaction of reducing sugars with the amino groups of macromolecules. AGEs accumulate in …

There is a growing body of evidence that cumulative hyperglycemic exposure plays a central
role in the development and progression of atherosclerotic cardiovascular disease in …

Advanced glycation end products (AGEs) are a heterogeneous group of molecules that
accumulate in plasma and tissues with advancing age, diabetes, and renal failure. There is …

Advanced glycation end‑products (AGEs) are proteins or lipids glycated nonenzymatically
by glucose, or other reducing sugars and their derivatives, such as glyceraldehyde …

The nonenzymatic glycation of proteins by aldehyde or keto-groups of reducing sugars, in a
process known as the Maillard reaction, eventually leads to the formation of advanced …

A non-enzymatic reaction between ketones or aldehydes and the amino groups of proteins,
lipids and nucleic acids contributes to the aging of macromolecules and to the development …

Advanced glycation end products (AGE) form via the Maillard reaction in vivo and are also
consumed from exogenous sources such as diet and smoking. They alter the structure and …

Glycation is a major cause of spontaneous damage to proteins in physiological systems.
This is exacerbated in diabetes as a consequence of the increase in glucose and other …