Cigarette smoke is a rich source of free radicals that can promote oxidative stress and
carcinogenesis including head and neck squamous cell carcinoma (HNSCC) development; …

It is expected that in 2016, there will be an estimated 48,330 new cases and 9,570 deaths
due to oral cancer in the US, which is about one person every hour every day. Due to the …

Black raspberries (BRB) demonstrate potent inhibition of aerodigestive tract carcinogenesis
in animal models. However, translational clinical trials evaluating the ability of BRB …

Oral cancer continues to be a significant public health problem worldwide. Recently
conducted clinical trials demonstrate the ability of black raspberries (BRBs) to modulate …

Oxidative stress has been implicated in the pathophysiology of chronic diseases and
cigarette smoking is known to be one of the major sources of oxidants. In this study, we …

Abstract Effects of black raspberry (BRB) extract and protocatechuic acid (PCA) on DNA
adduct formation and mutagenesis induced by metabolites of dibenzo [a, l] pyrene (DBP) …

Dietary intervention of freeze-dried black raspberries (BRBs) in a group of human colorectal
cancer patients has demonstrated beneficial effects, including proapoptosis …

The effect of administration of Korean black raspberry (BR) to smokers was assessed by 1 H
nuclear magnetic resonance (NMR) coupled with multivariate statistical analysis. In this …

Head and neck squamous cell carcinomas (HNSCC) are one of the most diagnosed
malignancies globally, with a 5-year survival rate of approximately 40% to 50%. Current …

We previously showed that metabolic activation of the environmental and tobacco smoke
constituent dibenzo [a, l] pyrene (DB [a, l] P) to its active fjord region diol epoxide (DB [a, l] …