SARS-CoV-2 Nanovaccine Composed of Microfluidic-Produced Gold Nanoparticles Induces Neutralizing Immune Responses

NC Dalibera, MJ Rodrigues-Jesus… - ACS Applied Nano …, 2023 - ACS Publications
The pursuit of effective and safe vaccines against severe acute respiratory syndrome caused
by SARS-CoV-2 has posed a significant challenge for science in recent years, allowing the …

Synthesis and immunogenicity assessment of a gold nanoparticle conjugate for the delivery of a peptide from SARS-CoV-2

S Farfán-Castro, MJ García-Soto… - … , Biology and Medicine, 2021 - Elsevier
The development of vaccines is a crucial response against the COVID-19 pandemic and
innovative nanovaccines could increase the potential to address this remarkable challenge …

[HTML][HTML] Gold Nanoparticle Virus-like Particles Presenting SARS-CoV-2 Spike Protein: Synthesis, Biophysical Properties and Immunogenicity in BALB/c Mice

VA Salazar, J Comenge, R Suárez-López, JA Burger… - Vaccines, 2024 - mdpi.com
Gold nanoparticles (AuNPs) decorated with antigens have recently emerged as promising
tools for vaccine development due to their innate ability to provide stability to antigens and …

Synthesis and evaluation of gold nanoparticles conjugated with five antigenic peptides derived from the spike protein of SARS-CoV-2 for vaccine development

S Farfán-Castro, MJ García-Soto… - Frontiers in …, 2024 - frontiersin.org
Introduction: The development of innovative anti-COVID-19 vaccines is a need to ensure the
population's immunity worldwide, with broad protection against variants of concern and low …

Bovine serum albumin-protected gold nanoclusters for sensing of SARS-CoV-2 antibodies and virus

Q Shen, F Hossain, C Fang, T Shu… - … Applied Materials & …, 2023 - ACS Publications
An approach to assess severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection (and past infection) was developed. For virus detection, the SARS-CoV-2 virus …

A receptor-binding domain-based nanoparticle vaccine elicits durable neutralizing antibody responses against SARS-CoV-2 and variants of concern

IJ Lee, YH Lan, PY Wu, YW Wu, YH Chen… - Emerging Microbes & …, 2023 - Taylor & Francis
Numerous vaccines have been developed to address the current COVID-19 pandemic, but
safety, cross-neutralizing efficacy, and long-term protectivity of currently approved vaccines …

Rapid development of SARS-CoV-2 spike protein receptor-binding domain self-assembled nanoparticle vaccine candidates

YF Kang, C Sun, Z Zhuang, RY Yuan, Q Zheng, JP Li… - ACS …, 2021 - ACS Publications
The coronavirus disease pandemic of 2019 (COVID-19) caused by the novel SARS-CoV-2
coronavirus resulted in economic losses and threatened human health worldwide. The …

Multivalent nanoparticle-based vaccines protect hamsters against SARS-CoV-2 after a single immunization

S Chiba, SJ Frey, PJ Halfmann, M Kuroda… - Communications …, 2021 - nature.com
The COVID-19 pandemic continues to wreak havoc as worldwide SARS-CoV-2 infection,
hospitalization, and death rates climb unabated. Effective vaccines remain the most …

Scalable biomimetic SARS-CoV‑2 nanovaccines with robust protective immune responses

X Chen, T Shi, C Yang, F Chen, X He… - Signal transduction and …, 2022 - nature.com
The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection requires rapid development of vaccines matching the pace of virus mutation. While …

[HTML][HTML] Nanoparticle vaccines based on the receptor binding domain (RBD) and heptad repeat (HR) of SARS-CoV-2 elicit robust protective immune responses

X Ma, F Zou, F Yu, R Li, Y Yuan, Y Zhang, X Zhang… - Immunity, 2020 - cell.com
Various vaccine strategies have been proposed in response to the global COVID-19
pandemic, each with unique strategies for eliciting immune responses. Here, we developed …