Overexpression of AXL on macrophages associates with disease severity and recurrence in chronic rhinosinusitis with nasal polyps

T Wang, Y Chen, R Gao, J Shui, B Xie - International Immunopharmacology, 2023 - Elsevier
Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by high
tissue heterogeneity and risk of postoperative recurrence, but the underlying mechanisms …

Elevated ALCAM expression associated with endotypes and postoperative recurrence in chronic rhinosinusitis with nasal polyps

H Zhang, S Xie, R Fan, F Wang, Z Xie… - Journal of inflammation …, 2022 - Taylor & Francis
Background Chronic rhinosinusitis with polyps (CRSwNP) is characterized by high
heterogeneity and postoperative recurrence rate. This study aimed to explore the clinical …

Down Regulation of EGF and AZGP1 Were Associated with Clinical Characteristics in Chronic Rhinosinusitis with Nasal Polyps: An Observation Study

P Jin, Q Zhang, Y Zang, L Zhao, H Zhang… - Journal of …, 2023 - Taylor & Francis
Objective The mechanisms underlying the chronic rhinosinusitis with nasal polyps
(CRSwNP) remained unclear. This study aimed to identify differentially expressed genes …

[HTML][HTML] Serum proteomics identify CSF1R as a novel biomarker for postoperative recurrence in chronic rhinosinusitis with nasal polyps

Y Niu, S Cao, M Luo, J Ning, N Wen, H Wu - World Allergy Organization …, 2024 - Elsevier
Background Chronic rhinosinusitis with nasal polyps (CRSwNP) presents a high rate of
postoperative recurrence, but its recurrent mechanisms are not fully clarified. In this study …

The roles of autophagy, mitophagy, and the Akt/mTOR pathway in the pathogenesis of chronic rhinosinusitis with nasal polyps

C Wang, ML Zhou, YC Liu… - Journal of Immunology …, 2022 - Wiley Online Library
The pathogenesis of CRSwNP is complex and unclear. CRSwNP is subdivided into two
types based on the infiltration of EOSs: eCRSwNP and noeCRSwNP. This study was …

Multiple cytokine analyses identify CSF1 as a robust biomarker for predicting postoperative recurrence in chronic rhinosinusitis with nasal polyps

Y Niu, S Cao, X Ma, Z Xu, H Wu - International Immunopharmacology, 2024 - Elsevier
Objective Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous disease
with a high rate of postoperative recurrence. This study aimed to discover potential …

[HTML][HTML] Immune cell infiltration and related core genes expression characteristics in eosinophilic and non‑eosinophilic chronic rhinosinusitis with nasal polyps

G Xiong, X Xie, Q Wang, Y Zhang… - Experimental and …, 2020 - spandidos-publications.com
Chronic rhinosinusitis with nasal polyps (CRSwNP) refers to chronic inflammation of the
sinonasal mucosa. It can either be eosinophilic (ECRSwNP) or non‑eosinophilic (non …

[HTML][HTML] Distinct type 2-high inflammation associated molecular signatures of chronic rhinosinusitis with nasal polyps with comorbid asthma

M Wang, X Bu, G Luan, L Lin, Y Wang, J Jin… - Clinical and translational …, 2020 - Springer
Background Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) and comorbid
asthma have more severe disease and are difficult to treat. However, the molecular …

Expression and role of BAG-1 in eosinophilic and non-eosinophilic chronic rhinosinusitis with nasal polyps

D Lin, H Lin, X Xiong - Inflammation, 2014 - Springer
The pathogenesis of human eosinophilic and non-eosinophilic chronic rhinosinusitis with
nasal polyps (ECRSwNP and nECRSwNP) remains undetermined. We aimed to investigate …

Reduced expression of antimicrobial protein secretory leukoprotease inhibitor and clusterin in chronic rhinosinusitis with nasal polyps

Y Huang, M Wang, Y Hong, X Bu… - Journal of …, 2021 - Wiley Online Library
Introduction. Antimicrobial peptides and proteins (AMPs) constitute the first line of defense
against pathogenic microorganisms in the airway. The association between AMPs and …