Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT)

Z Wang, S Hill, JM Luther, DL Hachey, KL Schey - Proteomics, 2012 - Wiley Online Library
Exosomes are membrane vesicles that are secreted by cells upon fusion of multivesicular
bodies with the plasma membrane. Exosomal proteomics has emerged as a powerful …

Proteomics characterization of exosome cargo

KL Schey, JM Luther, KL Rose - Methods, 2015 - Elsevier
Abstract Characterization of exosomal cargo is of significant interest because this cargo can
provide clues to exosome biogenesis, targeting, and cellular effects and may be a source of …

Isolation and mass spectrometry analysis of urinary extraexosomal proteins

S Hildonen, E Skarpen, TG Halvorsen, L Reubsaet - Scientific reports, 2016 - nature.com
The aim of the present study was to develop a LC-MS/MS-based proteomic analysis method
of urinary exosomal proteins that has the potential to discover disease biomarkers. In short …

Urinary exosomes and proteomics

PG Moon, S You, JE Lee, D Hwang… - Mass spectrometry …, 2011 - Wiley Online Library
A number of highly abundant proteins in urine have been identified through proteomics
approaches, and some have been considered as disease‐biomarker candidates. These …

[HTML][HTML] A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes

DAA Raj, I Fiume, G Capasso, G Pocsfalvi - Kidney international, 2012 - Elsevier
Urinary exosomes have received considerable attention as a potential biomarker source for
the diagnosis of renal diseases. Notwithstanding, their use in protein biomarker research is …

A new urinary exosome enrichment method by a combination of ultrafiltration and TiO 2 nanoparticles

X Xiang, F Guan, F Jiao, H Li, W Zhang, Y Zhang… - Analytical …, 2021 - pubs.rsc.org
Exosomes are small membrane-bound vesicles secreted by most cell types and play an
important role in cell-to-cell communication. Increasing evidence shows that exosomal …

Urinary exosomal proteins as (pan‐) cancer biomarkers: insights from the proteome

LA Erozenci, F Böttger, IV Bijnsdorp… - FEBS letters, 2019 - Wiley Online Library
Exosomes are extracellular vesicles (EV s) released from cells under both physiological and
pathological conditions, and may, thus, be present in biofluids. Urine is one of the most …

Proteomics analysis of bladder cancer exosomes

JL Welton, S Khanna, PJ Giles, P Brennan… - Molecular & cellular …, 2010 - ASBMB
Exosomes are nanometer-sized vesicles, secreted by various cell types, present in
biological fluids that are particularly rich in membrane proteins. Ex vivo analysis of …

A guide to mass spectrometric analysis of extracellular vesicle proteins for biomarker discovery

I Jalaludin, DM Lubman, J Kim - Mass Spectrometry Reviews, 2023 - Wiley Online Library
Exosomes (small extracellular vesicles) in living organisms play an important role in
processes such as cell proliferation or intercellular communication. Recently, exosomes …

Advances in membranous vesicle and exosome proteomics improving biological understanding and biomarker discovery

F Raimondo, L Morosi, C Chinello, F Magni… - …, 2011 - Wiley Online Library
Exosomes are membranous vesicles released by cells in extracellular fluids: they have been
found and analyzed in blood, urine, amniotic fluid, breast milk, seminal fluid, saliva and …