[HTML][HTML] B cell-intrinsic epigenetic modulation of antibody responses by dietary fiber-derived short-chain fatty acids
HN Sanchez, JB Moroney, H Gan, T Shen, JL Im… - Nature …, 2020 - nature.com
Short-chain fatty acids (SCFAs) butyrate and propionate are metabolites from dietary fiber's
fermentation by gut microbiota that can affect differentiation or functions of T cells …
fermentation by gut microbiota that can affect differentiation or functions of T cells …
[HTML][HTML] Gut microbial metabolites fuel host antibody responses
Antibody production is a metabolically demanding process that is regulated by gut
microbiota, but the microbial products supporting B cell responses remain incompletely …
microbiota, but the microbial products supporting B cell responses remain incompletely …
Short-chain fatty acids: linking diet, the microbiome and immunity
The short-chain fatty acids (SCFAs) butyrate, propionate and acetate are microbial
metabolites and their availability in the gut and other organs is determined by environmental …
metabolites and their availability in the gut and other organs is determined by environmental …
[HTML][HTML] The Microbial Metabolite Butyrate Induces Expression of Th1-Associated Factors in CD4+ T Cells
Short-chain fatty acids (SCFAs), which are generated by the bacterial fermentation of dietary
fibers, promote expansion of regulatory T cells (Tregs). Potential therapeutic value of SCFAs …
fibers, promote expansion of regulatory T cells (Tregs). Potential therapeutic value of SCFAs …
Butyrate directly decreases human gut lamina propria CD4 T cell function through histone deacetylase (HDAC) inhibition and GPR43 signaling
JJ Kibbie, SM Dillon, TA Thompson, CM Purba… - Immunobiology, 2021 - Elsevier
An important function of the gut microbiome is the fermentation of non-digestible dietary
fibers into short chain fatty acids (SCFAs). The three primary SCFAs: acetate, propionate …
fibers into short chain fatty acids (SCFAs). The three primary SCFAs: acetate, propionate …
[HTML][HTML] Control of lymphocyte functions by gut microbiota-derived short-chain fatty acids
CH Kim - Cellular & molecular immunology, 2021 - nature.com
A mounting body of evidence indicates that dietary fiber (DF) metabolites produced by
commensal bacteria play essential roles in balancing the immune system. DF, considered …
commensal bacteria play essential roles in balancing the immune system. DF, considered …
[HTML][HTML] Butyrate and propionate inhibit antigen-specific CD8+ T cell activation by suppressing IL-12 production by antigen-presenting cells
Short chain fatty acids (SCFAs), such as acetate, butyrate and propionate, are products of
microbial macronutrients fermentation that distribute systemically and are believed to …
microbial macronutrients fermentation that distribute systemically and are believed to …
[HTML][HTML] Regulation of the effector function of CD8+ T cells by gut microbiota-derived metabolite butyrate
M Luu, K Weigand, F Wedi, C Breidenbend, H Leister… - Scientific reports, 2018 - nature.com
The gut microbiota produces metabolites such as short-chain fatty acids (SCFAs) that
regulate the energy homeostasis and impact on immune cell function of the host. Recently …
regulate the energy homeostasis and impact on immune cell function of the host. Recently …
[HTML][HTML] Butyrate Conditions Human Dendritic Cells to Prime Type 1 Regulatory T Cells via both Histone Deacetylase Inhibition and G Protein-Coupled Receptor …
MMM Kaisar, LR Pelgrom, AJ Van der Ham… - Frontiers in …, 2017 - frontiersin.org
Recently, it has become clear that short-chain fatty acids (SCFAs), and in particular butyrate,
have anti-inflammatory properties. Murine studies have shown that butyrate can promote …
have anti-inflammatory properties. Murine studies have shown that butyrate can promote …
[PDF][PDF] Gut microbiota-derived short-chain fatty acids, T cells, and inflammation
CH Kim, J Park, M Kim - Immune network, 2014 - synapse.koreamed.org
T cells are central players in the regulation of adaptive immunity and immune tolerance. In
the periphery, T cell differentiation for maturation and effector function is regulated by a …
the periphery, T cell differentiation for maturation and effector function is regulated by a …