Atrial fibrillation (AF) is the most common sustained clinical arrhythmia and is associated
with significant morbidity, mostly secondary to heart failure and stroke, and an estimated two …

The pathophysiology of atrial fibrillation (AF) remains incompletely understood, despite its
prevalence and contributing role in stroke and heart failure. Whereas previous studies have …

Current evidence suggests that the pathogenesis of atrial fibrillation (AF) is multifactorial.
The observation that AF, once present, alters the electrophysiologic properties of the atrial …

Atrial fibrillation (AF) is an important cause of stroke and risk factor for heart failure and
death. Current pharmacologic treatments for AF have limited efficacy, and treatments that …

Atrial fibrillation (AF), the most prevalent arrhythmia, is often associated with enhanced
inflammatory response. Emerging evidence points to a causal role of inflammatory signaling …

The fundamental mechanisms governing the perpetuation of atrial fibrillation (AF), the most
common arrhythmia seen in clinical practice, are poorly understood, which explains in part …

Atrial fibrillation (AF) is the most common cardiac arrhythmia. However, the development of
preventative therapies for AF has been disappointing. The infiltration of immune cells and …

Inflammation has been implicated in the pathophysiology of atrial fibrillation (AF) and
mediates various pathologic processes such as oxidative stress and apoptosis. Atrial fibrosis …

Intensive research over the last few decades has seen significant advances in our
understanding of the complex mechanisms underlying atrial fibrillation (AF). The epidemic of …

Atrial fibrillation (AF) is one of the most common arrhythmias encountered in clinical practice.
AF is a major risk factor for stroke, which is associated with high mortality and great disability …