Glycan-specific molecularly imprinted polymers towards cancer diagnostics: merits, applications, and future perspectives
P Li, Z Liu - Chemical Society Reviews, 2024 - pubs.rsc.org
Aberrant glycans are a hallmark of cancer states. Notably, emerging evidence has
demonstrated that the diagnosis of cancers with tumour-specific glycan patterns holds great …
demonstrated that the diagnosis of cancers with tumour-specific glycan patterns holds great …
Molecularly imprinted polymers outperform lectin counterparts and enable more precise cancer diagnosis
J Pang, P Li, H He, S Xu, Z Liu - Chemical Science, 2022 - pubs.rsc.org
Accurately analysing the particular glycosylation status of protein biomarkers is of significant
importance in the precise, early diagnosis of cancer. Existing methods mainly rely on the use …
importance in the precise, early diagnosis of cancer. Existing methods mainly rely on the use …
[HTML][HTML] Molecular imprinting of glycoproteins: From preparation to cancer theranostics
Glycoprotein imprinted polymers have rapidly grown as excellent receptors for cancer
targeting, diagnostics, inhibition, and nanomedicines as they specifically target glycans and …
targeting, diagnostics, inhibition, and nanomedicines as they specifically target glycans and …
Solid-phase synthesis of molecularly imprinted polymer nanolabels: Affinity tools for cellular bioimaging of glycans
PX Medina Rangel, S Laclef, J Xu… - Scientific reports, 2019 - nature.com
Hyaluronic acid (HA) is a glycosaminoglycan that plays many roles in health and disease
and is a key biomarker of certain cancers. Therefore, its detection at an early stage, by …
and is a key biomarker of certain cancers. Therefore, its detection at an early stage, by …
Molecularly imprinted polymers: Antibody mimics for bioimaging and therapy
Molecularly imprinted polymers (MIPs) are tailor-made chemical receptors that recognize
and bind target molecules with a high affinity and selectivity. MIPs came into the spotlight in …
and bind target molecules with a high affinity and selectivity. MIPs came into the spotlight in …
Precision imprinting of glycopeptides for facile preparation of glycan-specific artificial antibodies
Z Bie, R Xing, X He, Y Ma, Y Chen, Z Liu - Analytical chemistry, 2018 - ACS Publications
Antibodies specific to glycans are essential in many areas for many important fields,
including disease diagnostics, therapeutics, and fundamental researches. However, due to …
including disease diagnostics, therapeutics, and fundamental researches. However, due to …
A glycoform‐resolved dual‐modal ratiometric immunoassay improves the diagnostic precision for hepatocellular carcinoma
P Li, J Pang, S Xu, H He, Y Ma… - Angewandte Chemie …, 2022 - Wiley Online Library
The glycosylation pattern of alpha fetoprotein (AFP) paves the basis for precise early
diagnosis of hepatocellular carcinoma (HCC). However, existing analytical methods ignore …
diagnosis of hepatocellular carcinoma (HCC). However, existing analytical methods ignore …
Efficient screening of glycan-specific aptamers using a glycosylated peptide as a scaffold
W Li, Y Ma, Z Guo, R Xing, Z Liu - Analytical Chemistry, 2020 - ACS Publications
Abnormal glycan structures are valuable biomarkers for disease states; the development of
glycan-specific binders is thereby significantly important. However, the structural homology …
glycan-specific binders is thereby significantly important. However, the structural homology …
Recognition and analysis of biomarkers in tumor microenvironments based on promising molecular imprinting strategies with high selectivity
JY He, Q Li, HX Xu, QY Zheng, QH Zhang… - TrAC Trends in …, 2023 - Elsevier
Rapidly and selectively detecting and analyzing biomarkers are important objectives for
diagnosis, therapy, and prognosis of different malignant tumors. Due to the complexity and …
diagnosis, therapy, and prognosis of different malignant tumors. Due to the complexity and …
Sialic acid-imprinted fluorescent core–shell particles for selective labeling of cell surface glycans
S Shinde, Z El-Schich… - Journal of the …, 2015 - ACS Publications
The expression of cell surface glycans terminating with sialic acid (SA) residues has been
found to correlate with various disease states there among cancer. We here report a novel …
found to correlate with various disease states there among cancer. We here report a novel …