Objective This study examined the in vitro effect of melatonin on the protein synthesis of
mitochondria, as well as autophagy in matured oocytes of aged mice. Materials and …

Melatonin (MT) can improve the effect of cryopreservation on oocytes by suppressing
oxidative stress and maintaining the permeability of the oolemma. In this study, MT was …

With increase in women's age, the reproductive capability of female mammals decreases
dramatically caused by age-related oxidative stress, coinciding with the decline in the …

The physiology of oocyte in vitro maturation remains elusive. Generally, the oocytes have a
very low maturation rate under in vitro conditions. In the current study, we found that …

Aims Previous reports have demonstrated that melatonin exists in multiple extrapineal sites,
and higher amounts of melatonin are present in human follicular fluid than in serum, which …

The quality of postovulatory metaphase II oocytes undergoes a time-dependent deterioration
as a result of the aging process. Melatonin is considered to be an anti-aging agent …

Melatonin, the major pineal secretory product, has a significant impact on the female
reproductive system. Recently, the beneficial effects of melatonin on mammalian oocyte …

Previous studies have demonstrated that melatonin could ameliorate oxidative stress during
the cryopreservation of mouse MII oocytes and their in vitro culture after parthenogenetic …

Cryopreservation causes cryoinjury to oocytes and impairs their developmental
competence. Melatonin (MLT) can improve the effect of cryopreservation in animal oocytes …

If fertilization does not occur for a prolonged period in vivo or in vitro, the postovulatory
oocytes will deteriorate, which called the postovulatory aging. This process disrupts the …